PA 1

Question 1

What is in the sample?

Answer 1

Qualitative

Question 2

How much is present in the sample?

Answer 2

Quantitative

Question 3

Sum of all factors which contribute
directly or indirectly to the safety,
effectiveness, and reliability of the
product

Answer 3

Quality

Question 4

Ensures that drug products are
designed and produced to meet or
exceed customer requirements for
effect and safety

Answer 4

Quality

Question 5

Types of analysis

Answer 5

Based on sample size
Based on extent of determination
Based on nature of methods

Question 6

Total amount of a CLASS or GROUP of active constituents

Answer 6

Proximate

Question 7

Amount of a SINGLE CHEMICAL SPECIES in a sample

Answer 7

Ultimate

Question 8

A book of public pharmacopeial
standards

Answer 8

USP/NF

Question 9

generic or non- proprietary name of the
drug

Answer 9

Official title

Question 10

a formula which shows the arrangement of the elements

Answer 10

Structural formula

Question 11

the simplest formula

Answer 11

Empirical formula

Question 12

overall weight of the compound

Answer 12

Molecular weight

Question 13

Code numbers assigned by CAS to the chemical substance

Answer 13

Chemical Abstracts Service Number

Question 14

Include names based on other systems of
nomenclature or naming like IUPAC

Answer 14

Other chemical names

Question 15

A statement of purity and composition of the compound or drug which has been predetermined by the Pharmacopeia to be the purity

Answer 15

Official definition

Question 16

the degree to which information
matches true or accepted values

Answer 16

Accuracy

Question 17

degree to which measurements
fluctuates around a central measurement

Answer 17

Precision

Question 18

manifest themselves by slight variations in a series of observations
made by the observer under identical conditions

Answer 18

Indeterminate errors

Question 19

Possible to partially determine their
value and reduce their effect on the
final result

Answer 19

Determinate errors

Question 20

a method of analysis
that determines the precise endpoint
of a reaction and therefore the
precise quantity of reactant in the
titration flask

Answer 20

Titration

Question 21

Volumetric or standard solution of known concentration

Answer 21

Titrant

Question 22

the active constituent to be analyzed

Answer 22

Analyte

Question 23

Chemicals capable of changing at or near the endpoint

Answer 23

Indicators

Question 24

Point when added titrant is chemically equivalent to the analyte in the sample

Answer 24

Equivalence point

Question 25

Experimental approximate of the equivalence point

Answer 25

Endpoint

Question 26

the mathematical formula employed in the calculation to find the quantity of the constituent being analyzed

Answer 26

Stoichiometry

Question 27

grams of substance that is chemically equivalent to 1 mL of a volumetric solution

Answer 27

Titer

Question 28

a solution whose accurate concentration is known

Answer 28

Standard solution

Question 29

another standard solution of known concentration

Answer 29

Secondary solution

Question 30

a carefully weighed sample of a substance of known concentration

Answer 30

Primary solution

Question 31

the number of equivalents of solute per liter of solution

Answer 31

Normality

Question 32

the number of moles of solute per liter of solution

Answer 32

Molarity

Question 33

the number of moles of solute per 1000 g of solvent

Answer 33

Molality

Question 34

process of establishing the accurate concentration of a solution by allowing it to react with a pure substance known as primary standard

Answer 34

Standardization

Question 35

acidic titrant with basic analyte

Answer 35

Acidimetry

Question 36

basic titrant with acidic analyte

Answer 36

Alkalimetry

Question 37

conducted by introducing a standard acid/ base solution gradually from a buret into a solution of the base/ acid being assayed until chemically equivalent amounts of each have reacted as shown by some change in properties of the mixture

Answer 37

Direct Titration

Question 38

carried out by dissolving the substance under examination in an accurately measured quantity of standard solution known to be in excess and titrating the excess of the latter with another standard solution

Answer 38

Residual Titration

Question 39

developed by a Danish chemist named Johan Kjeldahl in 1883. This method was specifically developed for determining the nitrogen contents in organic and inorganic substances

Answer 39

Kjeldahl method