Pads VIII Flashcards

(55 cards)

1
Q
A
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2
Q

Describe the clinical features of OCD [+]

A

Obsessive Themes:
* Contamination fears: Fear of becoming contaminated by germs, dirt, or harmful substances.
* Harm-related obsessions: Fear of causing harm to oneself or others due to negligence or unintentional actions.
* Unwanted sexual thoughts: Intrusive and distressing sexual thoughts or images involving inappropriate behaviours.
* Religious/moral obsessions: Excessive concern with religious or moral issues, also known as scrupulosity.
* Perfectionism/symmetry: Intense need for orderliness, symmetry, or exactness.

Compulsive Behaviors:
* Cleaning/washing: Excessive handwashing, showering, cleaning of objects, etc., in response to contamination fears.
* Checking rituals: Repeatedly checking doors, appliances, etc., to ensure safety and prevent harm.
* Counting/repeating rituals: Performing mental acts (e.g., counting) or repeating actions a specific number of times to reduce anxiety.
* Ordering/arranging behaviours: Arranging objects in a particular manner or following strict routines to achieve a sense of orderliness and control.
* Mental neutralizing strategies: Attempting to counteract intrusive thoughts with other thoughts (e.g., prayer) in an effort to alleviate distress.

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3
Q

Which assessment tools can be used to dx OCD? [2]

A

Yale-Brown Obsessive-Compulsive Scale (Y-BOCS): A widely used clinician-administered scale that measures the severity of obsessions and compulsions.

Obsessive-Compulsive Inventory-Revised (OCI-R): A self-report questionnaire assessing the severity of various OCD symptoms.

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4
Q

Describe the management of mild, moderate and severe OCD [+]

A

If functional impairment is mild
low-intensity psychological treatments:

* cognitive behavioural therapy (CBT) including exposure and response prevention (ERP)
* If this is insufficient or can’t engage in psychological therapy, then offer choice of either a course of an SSRI or more intensive CBT (including ERP)

If moderate functional impairment
* offer a choice of either a course of an SSRI (any SSRI for OCD but fluoxetine specifically for body dysmorphic disorder) or more intensive CBT (including ERP)

If severe functional impairment
* offer combined treatment with an SSRI and CBT (including ERP)

NB: These notes are for adults

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5
Q

How long is the tx for OCD for if effective? [1]

A

if treatment with SSRI is effective then continue for at least 12 months to prevent relapse and allow time for improvement
- If SSRI ineffective or not tolerated try either another SSRI

NB: depression / anxiety is 6 months

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6
Q

What are medical causes of anxiety disorders? [3]

A

Hyperthyroidism
cardiac disease
medication-induced anxiety
- salbutamol
- theophylline
- corticosteroids
- antidepressants
- caffeine

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7
Q

What is the drug tx for GAD?

A

NICE suggest sertraline should be considered the first-line SSRI
- if sertraline is ineffective, offer an alternative SSRI or a serotonin-noradrenaline reuptake inhibitor (SNRI)
- examples of SNRIs include duloxetine and venlafaxine

If the person cannot tolerate SSRIs or SNRIs
- consider offering pregabalin
- interestingly for patients under the age of 30 years NICE recommend you warn patients of the increased risk of suicidal thinking and self-harm.
- Weekly follow-up is recommended for the first month

NB - this is for adults

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8
Q

Describe the 5 step approach to the management of panic disorder? [5]

A

Again a stepwise approach:
step 1: recognition and diagnosis

step 2: treatment in primary care - see below
- NICE recommend either cognitive behavioural therapy or drug treatment
SSRIs are first-line.

- If contraindicated or no response after 12 weeks then imipramine or clomipramine should be offered

step 3: review and consideration of alternative treatments

step 4: review and referral to specialist mental health services

step 5: care in specialist mental health services

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9
Q

Describe the physiological abnormalities seen in anorexia nervosa [+]

A
  • hypokalaemia
  • low FSH, LH, oestrogens and testosterone
  • raised cortisol and growth hormone
  • impaired glucose tolerance
  • hypercholesterolaemia
  • hypercarotinaemia
  • low T3
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10
Q

Describe the dx of AN [

A

Diagnosis is now based on the DSM 5 criteria. Note that BMI and amenorrhoea are no longer specifically mentioned:
1. Restriction of energy intake relative to requirements leading to a significantly low body weight in the context of age, sex, developmental trajectory, and physical health.
2. Intense fear of gaining weight or becoming fat, even though underweight.
3. Disturbance in the way in which one’s body weight or shape is experienced, undue influence of body weight or shape on self-evaluation, or denial of the seriousness of the current low body weight.

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11
Q

What is the treatment plans for children / YAs [2] and adults [2] for anorexia

A

In children and young people
- NICE recommend ‘anorexia focused family therapy’ as the first-line treatment.
- The second-line treatment is cognitive behavioural therapy.

For adults with anorexia nervosa, NICE recommend we consider one of:
- individual eating-disorder-focused cognitive behavioural therapy (CBT-ED)
- Maudsley Anorexia Nervosa Treatment for Adults (MANTRA)
- specialist supportive clinical management (SSCM).

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12
Q

What are the cardiac complications of anorexia? [4]

A

bradycardia
hypotension
prolonged QT interval, increasing the risk of sudden cardiac death
Mitral valve prolapse may also occur.

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13
Q

Describe the GII abnormalities see in anorexia [4]

A

Gastroparesis, constipation, and liver dysfunction are frequently observed. Superior mesenteric artery syndrome may also develop.

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14
Q

The severity of Bulimia nervosa is also categorised based on the frequency of inappropriate compensatory behaviours (as per DSM-5):

What determines mild, moderate, severe and extreme bulimia? [4]

A

Mild: An average of 1-3 episodes per week.
Moderate: An average of 4-7 episodes per week.
Severe: An average of 8-13 episodes per week.
Extreme: An average of 14 or more episodes per week.

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15
Q

Describe the investigations used for BN

A

Psychological Assessment
- Semi-structured interviews: The Eating Disorder Examination (EDE) is considered the gold standard for diagnosing eating disorders including BN.
- Self-report questionnaires: Tools such as the Bulimia Test-Revised (BULIT-R) or Eating Disorders Inventory (EDI) can be used to supplement clinical interviews and provide additional information about symptom severity and related psychological features.

Laboratory Investigations
* FBC: anaemia or infection
* U&Es: hypokalaemia; AKIs
* LFTS: malnutrition or alcohol abuse

Radiological Investigations (not routine)
- DEXA scan
- Gastrointestinal imaging

ECG

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16
Q

Describe the dx of BN

A

The diagnostic criteria for Bulimia Nervosa, as per the ICD-10 and DSM-5, are outlined below. It’s imperative to note that these criteria are not exhaustive and should be used in conjunction with clinical judgement.

ICD-10 Criteria:
* A persistent preoccupation with eating, and an irresistible craving for food; the patient succumbs to episodes of overeating in which large amounts of food are consumed in short periods of time.
* The patient attempts to counteract the ‘fattening’ effects of food by induced vomiting, purgative abuse, alternating periods of starvation, or use of drugs such as appetite suppressants.
* If the disorder occurs in diabetic patients they may choose to neglect their insulin treatment.

DSM-5 Criteria:
* Recurrent episodes of binge eating characterised by both consuming an amount of food that is definitely larger than most people would eat during a similar period under similar circumstances and a sense of lack of control over eating during the episode.
* Recurrent inappropriate compensatory behaviours to** prevent weight gain such as self-induced vomiting; misuse of laxatives, diuretics or other medications; fasting; or excessive exercise.**
* The binge eating and inappropriate compensatory behaviours both occur, on average, at least once a week for three months.
* Self-evaluation is unduly influenced by body shape and weight.

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17
Q

Describe the management of BN [+]

A

Psychotherapy:
* Offer CBT-ED to adults with BN as it has been shown to reduce binge-eating and purging behaviours.
* If CBT-ED is not available or the patient declines, consider other forms of psychological therapy such as interpersonal psychotherapy or dialectical behaviour therapy.

Pharmacotherapy:
* Selective serotonin reuptake inhibitors (SSRIs), specifically fluoxetine, have been approved by the Food and Drug Administration for BN treatment. However, they should be used in conjunction with psychotherapy rather than standalone treatment.
* If SSRIs are contraindicated or not tolerated, consider other types of antidepressants like tricyclics or monoamine oxidase inhibitors after discussing potential side effects and monitoring requirements.

Dietetic Support:
* A registered dietitian can provide valuable input regarding meal planning and nutritional rehabilitation. They can also help address any distorted beliefs about food and weight.

Physical Health Monitoring:
* Routine monitoring of vital signs and electrolytes is crucial due to the risk of complications associated with purging behaviours. Electrocardiogram may be required in some cases.

Inpatient or Day Patient Care:
* Consider inpatient care for patients who are medically unstable or for whom outpatient treatment has failed. The goal should be to stabilise the patient’s physical health while continuing with psychotherapeutic interventions.

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18
Q

BN suffer which cardiac complication than those without? [1]

A

Mitral valve prolapse: This is a heart condition that affects the mitral valve’s function. It has been observed more frequently in individuals with bulimia nervosa than in those without.

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19
Q

Describe Salter-Harris Classification [5]

A

Use the SALTR mnemonic to remember the types:

Type 1: Straight across
Type 2: Above
Type 3: BeLow
Type 4: Through
Type 5: CRush

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20
Q

What is the overall principles of managing fractures in general [2]

A

The first principle is to achieve mechanical alignment of the fracture by:
* Closed reduction via manipulation of the joint
* Open reduction via surgery

The second principle is provide relative stability for a period of time, to allow healing. This can be done by fixing the bone in the correct position while it heals. There are various ways the bone can be fixed in position:
* External casts
* K wires
* Intramedullary wires
* Intramedullary nails
* Screws
* Plate and screws

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21
Q

TOM TIP: Examiners like to test your knowledge about the causes of hip pain in a child. It is worth being familiar with the differential diagnosis and distinguishing features of each cause.

What are they most likely to be depending on the age:

  • 0-4 [3]
  • 5-10 [3]
  • 10-16 [3]
A

0 – 4 years:
* Septic arthritis
* Developmental dysplasia of the hip (DDH)
* Transient sinovitis

5 – 10 years:
* Septic arthritis
* Transient sinovitis
* Perthes disease

10 – 16 years:
* Septic arthritis
* Slipped upper femoral epiphysis (SUFE)
* Juvenile idiopathic arthritis

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22
Q

Describe the clinical features of transient synovitis [5]

A

Hip pain
* This is most often unilateral however can present bilaterally
* The pain can radiate towards the groin and/or to the knee

Limp
* This may be noticed by parents as the child refusing to weight-bear (seen in >60% of children with transient synovitis)

Refusal to weight bear

Low-grade temperature (seen in 30% of children with transient synovitis)

Recent infection e.g. upper respiratory infection or a bacterial infection - particularly Streptococcal

It is important to note that children should otherwise be systemically well

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23
Q

What are the examination findings in transient synovitis [4]

A

The following signs are typical of transient synovitis:
Look
* Children will typically hold the leg in a flexed, abducted and externally rotated position - this position results in the least amount of intracapsular pressure within the joint and is therefore the least painful

Feel
* Tenderness on palpation of the hip joint

Move
* Limited internal rotation - this is the most sensitive range of movement test for transient synovitis
* Limp when asked to walk

Special manoeuvres- Log roll test
- The log roll test is carried out by asking the patient to lay supine with the hip and knee extended
* The examiner then passively rotates the entire limb internally and then externally
* A positive test is defined as involuntary muscle guarding when the leg is rolled passively

24
Q

How does transient synovitis present on xray? [1]

How does US of the hip present? [3]

A

Xray: normal

Ultrasound findings in transient synovitis can include intracapsular fluid, joint effusion and synovial thickening

25
NICE recommend that a child aged between 3-9 years with a working diagnosis of transient synovitis can be managed in primary care if: [3]
They are **afebrile**, **mobile** but **limping** and symptoms have been **present for < 48 hours**
26
Describe the management of transient synovitis [3]
**Conservative** * It is important to explain to parents the natural history of the condition and to provide adequate safety netting * For example - **we would expect the symptoms to resolve within 1 week with rest and simple pain relief. We would not expect the symptoms to worsen or the child to become systemically unwell (fever, lethargy, irritability).** If this does happen then you should take the child to the emergency department immediately as this could be a sign of a more serious pathology. * **Arrange a follow-up appointment after 48-hours to ensure symptoms are resolving** **Medical** - Simple analgesia using paracetamol or ibuprofen ## Footnote Typically there is a significant improvement in symptoms after 24 – 48 hours. Symptoms fully resolve within 1 – 2 weeks without any lasting problems. Transient synovitis may recur in around 20% of patients.
27
Catterall staging is used for Perthes disease. What are the 4 different stages? [4]
28
Describe the presentation of Perthes [4]
Perthes disease present with a slow onset of: * **Pain in the hip or groin** * **5-8 years old** * **Limp** * **Restricted hip movements** * There may be **referred pain to the knee** There will be NO history of trauma. If the pain is triggered by minor trauma, think about slipped upper femoral epiphysis, particularly in older children.
29
Describe the management of Perthes disease (conservative [4] and surgical [3]
**PM**: * If less than **6 years: observation** * Older: **surgical management with moderate results** * **Operate on severe deformities** **Conservative management:** - This includes **activity modification** - **Pain** **management** with analgesics or anti-inflammatory medications - **physical therapy** to maintain range of motion and muscle strength. - **Orthotic device**s, such as casts or braces, may be used to provide containment of the femoral head within the acetabulum. **Surgical management:** * Procedures include **femoral or pelvic osteotomies to improve hip joint congruence** * **arthrodiastasis** to decompress the hip joint * in severe cases, **hip arthroplasty.**
30
What would indicate surgical management for Perthes? [3]
Indications for surgery include **persistent pain, progressive deformity, or failed conservative management.**
31
What is chondromalacia and how do you differentiate this from OSD? [2]
**Chondromalacia patella** **Similarities**: - knee pain presenting in sporty teenagers, managed conservatively **Differences**: - typically presents with pain on anterior or inner side of the knee ## Footnote Chondromalacia patellae is a condition where there is damaged cartilage behind the patella (kneecap). It is like a softening or wear and tear of the cartilage.
32
How do you distinguish between OSD and **Osteochondritis dissecans**? [1]
**Osteochondritis dissecans** **Similarities**: - activity-related knee pain with localised bony tenderness **Differences**: - presents with mechanical features as knee intermittently locks and gives way. Effusion and joint crepitus present on examination
33
Describe what is meant by osteochondritis dissecans [1]
**Osteochondritis dissecans (OCD)** is a **pathological process affecting the subchondral bone** (most often in the knee joint) **with secondary effects on the joint cartilage, including pain, oedema, free bodies and mechanical dysfunctions.**
34
What are the clinical signs of osteochondritis dissecans [5]
**Joint effusion** **Full range of movement** in the joint without signs of ligamentous instability **External tibial rotation when walking** - if medial femoral involvement **Tenderness on palpation of the articular cartilage of the medial femoral condyle, when the knee is flexed** **Wilson's sign** for detecting medial condyle lesion - with the knee at 90° flexion and tibia internally rotated, the gradual extension of the joint leads to pain at about 30°, external rotation of the tibia at this point relieves the pain
35
Describe the investigations used for osteochondritis dissecans [4]
**X-ray** (anteroposterior, lateral and tunnel views) - may show the **subchondral crescent sign or loose bodies** **MRI** - used to evaluate cartilage, visualise loose bodies, stage and assess the stability of the lesion **CT** - may be used in preoperative planning and in cases where MRI is not available or contraindicated **Scintigraphy** - may be used to guide treatment as it may show increased uptake in the fragments - a sign of osteoblastic activity
36
Which endocrine abnormalities are associated with SUFE? [3]
**hypothyroidism, growth hormone supplementation and renal osteodystrophy**
37
The **[]** angle can also be used to quantify the degree of slippage in SCFE. It compares the angle between a line parallel to the physis and a line perpendicular to the shaft of the femur in both normal and affected hips. A greater angle indicates increased severity.
The **Southwick angle** can also be used to quantify the degree of slippage in SCFE. It compares the angle between a line parallel to the physis and a line perpendicular to the shaft of the femur in both normal and affected hips. A greater angle indicates increased severity.
38
Describe the presentation of SUFE
The typical exam presentation is an **adolescent, obese male undergoing a growth spurt.** There may be a history of **minor** **trauma** that **triggers the onset of symptoms**. Suspect SUFE if the **pain is disproportionate to the severity of the trauma.** Presenting symptoms can be vague. These can be: * **Hip, groin, thigh or knee pain** * **Restricted range of movement in the hip** * **Painful limp** * **11/12 year old** * When examining the patient, they will **prefer to keep the hip in external rotation.** **They will have limited movement of the hip, particularly restricted internal rotation.**
39
Describe the limited range of motion seen in hip movements of a child w SUFE [3]
There may be restriction in hip movements, especially **internal rotation, abduction and flexion**. Forced passive internal rotation often exacerbates the pain.
40
Describe the management of SUFE
The management of slipped capital femoral epiphysis (SCFE) is primarily surgical, aiming to stabilise the epiphysis and prevent further slippage. The specific management steps are as follows: **In Situ Pinning:** - This is the most common treatment for stable SCFE. A single screw or pin is inserted percutaneously into the femoral head to secure it in place. In unstable SCFE, multiple screws may be used. **Open Reduction and Internal Fixation (ORIF):** - In severe cases or when closed methods fail, open reduction followed by internal fixation can be performed. This involves surgically exposing the hip joint, realigning the displaced femoral head under direct vision and then securing it with screws. **Osteotomy**: - If there is significant deformity or chronic SCFE, an osteotomy may be required. This procedure involves cutting and realigning the bone to correct its position and orientation.
41
Describe the treatment plan for DDH [3+]
Treatment typically **involves a Pavlik harness** if the baby **presents at less than 6 months of age** - The Pavlik harness is **fitted and kept on permanently**, adjusting for the growth of the baby. - The aim is to **hold the femoral head in the correct position** to allow the hip socket (**acetabulum**) to **develop a normal shape**. - This harness keeps the **baby’s hips flexed and abducted**. - The child is regularly reviewed and the harness is removed when their hips are more stable, usually after 6 – 8 weeks. **Surgery** - is required when the harness fails or the diagnosis is **made after 6 months of age.** - After surgery is performed, an **hip spica cast** is used to immobilises the hip for a prolonged period. - **Open reduction:** **For children older than two years**, or when closed reduction is unsuccessful, surgical intervention in the form of an open reduction may be required. Additional procedures, such as femoral or pelvic osteotomies, may be needed to achieve optimal hip stability and congruity.
42
Describe which ages determine different treatment methods for DDH [3]
**Pavlik harness:** - Under 6 months **Closed reduction and spica casting:** - In infants aged six months to two years - or when Pavlik harness treatment fails **Open reduction**: - For children older than two years, or when closed reduction is unsuccessful
43
Describe early [3] and late [3] complications of DDH
**Early Complications:** **Osteonecrosis**: - This is one of the most severe early complications. It involves death of bone tissues due to limited blood flow, leading to femoral head deformity and growth disturbance. **Residual dysplasia**: - Despite adequate treatment, some patients may still exhibit residual dysplasia. This refers to persistent abnormality in the shape or position of the hip joint, predisposing it to premature degenerative changes. **Subluxation or dislocation:** - If not adequately treated or managed, DDH can result in subluxation (partial dislocation) or complete dislocation of the hip joint. **Late Complications:** **Osteoarthritis**: - Untreated or poorly managed DDH often leads to early onset osteoarthritis. This degenerative disease results from wear and tear on the hip joint over time, causing pain, stiffness and reduced mobility. **Gait abnormalities**: - These are common in individuals with untreated DDH. Abnormalities such as limping or waddling gait can affect mobility and quality of life. **Hip impingement:** - Also known as Femoroacetabular Impingement (FAI), this condition occurs when there's an abnormal contact between the femoral head and acetabulum. It can cause pain and limit movement in the hip joint.
44
Describe what is meant by calcaneal apophysitis [1]
is the **commonest** **cause** of **heel** **pain** in children and adolescents . It is an **overuse injury caused by micro-fractures of the calcaneal apophysis** at the **site of attachment of the Achilles tendon.**
45
Describe the clinical presentation of Calcaneal apophysitis (Sever's disease) [+]
It presents with **gradual onset heel pain** which may be **worse on standing and with activity**. It is typically **relieved by rest**. It can be **unilateral** but is often **bilateral** (60% of cases) Medial and lateral compression of the heel i.e '**squeezing**' causes **pain**. Pain on **ankle dorsiflexion**, especially on active toe raise **Mild heel swelling** **Calcaneal enlargement** * Only if chronic which is rare
46
Which red flag symptoms would indicate a patient wasn't suffering from calcaneal apophysitis [3]
Red flag features suggestive of an alternative diagnosis include **significant rest pain, night pain or large swelling.**
47
What is talipes? [1] What is talipes equinovarus? [1] What is talipes calcaneovalgus? [1]
**Talipes** is a fixed abnormal ankle position that presents at birth. It is also known as **clubfoot**. It can occur spontaneously or be associated with other syndromes. It is usually identified at birth or during the newborn examination. **Talipes equinovarus** describes the **ankle in plantar flexion and supination.** **Talipes calcaneovalgus** describes the **ankle in dorsiflexion and pronation.**
48
**Talipes** is treated with the “**[]** **method**” with good results.
Talipes is treated with the “**Ponseti method”** with good results. Surgery may be required if the Ponseti method fails or cannot be used.
49
Desribe the Ponseti method used to treat talipes
The Ponseti method is a way of treating talipes without surgery. It is usually very successful. **Treatment is started almost immediately after birth**. It is performed by a properly trained therapist. The foot is **manipulated towards a normal position and a cast is applied to hold it in position**. This is **repeated over and over until the foot is in the correct position**. At some point an **achilles tenotomy** to **release tension** in the **achilles tendon is performed, often in clinic**. **After treatment with the cast is finished a brace is used to hold the feet in the correct position when not walking until the child is around 4 years old.** This brace is sometimes referred to as “boots and bars”.
50
Describe what is meant by positional talipes [1] and how it is treated [1]
**Positional talipes** is a common condition where the **resting position of the ankle is in plantar flexion and supination**, however it is **not fixed in this position** and there is no structural boney issue in the ankle. - The muscles are **slightly tight around the ankle but the bones are unaffected**. This requires **referral** to a **physiotherapist** for some simple exercises to **help the foot return to a normal position**. Positional talipes will resolve with time.
51
Wheat is mneumonic for osteogenesis imperfecta presentation? [4]
**BITE** **B**ones fracture **I**(eye) blue sclera **T**eeth imperfections **E**ar hearing loss
52
Describe the management of osteogenesis imperfecta [2]
The underlying genetic condition cannot be cured. Medical treatments include: **Bisphosphates** to increase bone density **Vitamin D** supplementation to prevent deficiency **Management is done by the multidisciplinary team, with:** * Physiotherapy and occupational therapy to maximise strength and function * Paediatricians for medial treatment and follow up * Orthopaedic surgeons to manage fractures * Specialist nurses for advice and support * Social workers for social and financial support
53
Describe what causes achondroplasia [1] and how this presents [4]
The achondroplasia gene, **fibroblast growth factor receptor 3 (FGFR3)**, is on chromosome 4. - This results in **abnormal cartilage** **Presentation**: * **short** **limbs** (rhizomelia) with **shortened** **fingers** (brachydactyly) * **large head with frontal bossing and narrow foramen magnum** * **midface hypoplasia with a flattened nasal bridge** * **'trident' hands** * **lumbar lordosis** * **Bow legs** (genu varum)
54
Describe why people with achondroplasia have disproportionate skulls [2]
**Different areas** of the **skull grow by different methods**, some of which are affected more than others. The **skull base grows and fuses via endochondral ossification**, which is affected by **achondroplasia** and leads to a **flattened mid-face and nasal bridge and foramen magnum stenosis**. The **cranial vault grows** and **fuses via membranous ossification**, which is **unaffected** by **achondroplasia** and leads to a **normal sized vault and frontal bossing** (prominent forehead).
55
What are common associations that occur with achondroplasia? [5]
**Recurrent otitis media**, due to cranial abnormalities Kyphoscoliosis Spinal stenosis Obstructive sleep apnoea Obesity Foramen magnum stenosis can lead to **cervical cord compression and hydrocephalus**