Flashcards in Parvoviridae -- Human Parvovirus (B19) Deck (21):
Parvovirus claim to fame?
How many serotypes?
Most common symptom?
Rash in children
Mitotically active, especially erythroid lineage cells of bone marrow
Name of Erythrocyte P antigen
How does ssDNA become ds in the host?
Host DNA polymerases found in growing cells
Transcriptions/Replication/Assembly occur in....
Virus released by...
How does Parvo present?
Early -- Sore throat, fever, upset stomach, headache
Late -- Rash
Bonus adult complications?
How is the rash in Parvovirus often described?
Parvovirus infection in pregnancy associated with...
Increased Fetal Loss
What is fetal hydrops?
Edema of the fetus - symptoms include...
Anaemic heart failure
How is fetal hydrops often diagnosed?
Why is Parvovirus especially dangerous for anemic people?
Can cause a cessation of RBC production
Causes Aplastic Crisis
Symptoms of Aplastic Crisis?
Pale skin, lips, nails
Shortness of breath, headached, fever, fainting
How is Parvovirus transmitted?
Who typically gets parvovirus?
School-age and daycare kids