Path-Esoph Neoplasms Flashcards Preview

Gastrointestinal > Path-Esoph Neoplasms > Flashcards

Flashcards in Path-Esoph Neoplasms Deck (11):
1

two major malignancies of GI tract

squamous cell carcinoma; adenocarcinoma

2

histological features of squamous cell carcinoma

nests/cords of atypical squamous cells +/- keratin pearls, in desmoplastic stroma

3

histological features of adenocarcinoma

overexpansion of glands; look for dark masses with lumens

4

what are the three morphologies that most GI malignancies take?

fungating (=exophytic), infiltrating (through wall), and/or ulcerating (excavation)

5

which is more common: adeno or squamous cell carcinoma of the esophagus?

adenocarcinoma

6

most common location of adenocarcinoma

lower 1/3 of esophagus

7

almost all adenocarcinomas arise from?

Barrett's epithelium

8

etiologies of squamous cell carcinoma

EtOH, tobacco, esophageal dz, blacks have higher risk

9

most common location of squamous cell carcinoma

any 1/3 of esophagus

10

both squamous cell and adenocarcinoma of the esophagus can grow circumferentially, leading to?

stenosis and dysphagia

11

complications of esophageal malignancy include?

local infiltration, nodal mets, visceral mets