Flashcards in Path-Esoph Neoplasms Deck (11):
two major malignancies of GI tract
squamous cell carcinoma; adenocarcinoma
histological features of squamous cell carcinoma
nests/cords of atypical squamous cells +/- keratin pearls, in desmoplastic stroma
histological features of adenocarcinoma
overexpansion of glands; look for dark masses with lumens
what are the three morphologies that most GI malignancies take?
fungating (=exophytic), infiltrating (through wall), and/or ulcerating (excavation)
which is more common: adeno or squamous cell carcinoma of the esophagus?
most common location of adenocarcinoma
lower 1/3 of esophagus
almost all adenocarcinomas arise from?
etiologies of squamous cell carcinoma
EtOH, tobacco, esophageal dz, blacks have higher risk
most common location of squamous cell carcinoma
any 1/3 of esophagus
both squamous cell and adenocarcinoma of the esophagus can grow circumferentially, leading to?
stenosis and dysphagia