Path-IBD Flashcards Preview

Gastrointestinal > Path-IBD > Flashcards

Flashcards in Path-IBD Deck (14):
1

signs of active colitis

cryptitis, crypt abscess, ulceration

2

signs of chronic colitis

altered crypt architecture (dysarray, dropout, branching), inflammation in lamina propria

3

chronic active colitis is?

chronic colitis + neutrophils

4

normal lamina propria has (lowest/highest) inflammatory cell density at crypt bases

lowest

5

inflammatory cells that participate in chronic inflammation of lamina propria

lymphocytes, plasma cells, eosinophils

6

in chronic colitis, there are increased inflammatory cells at?

the base of crypts

7

common to have periods of exacerbation and remission

UC, CD (both)

8

increases risk of colon cancer

UC, CD (both)

9

gross features of UC (2 things)

pseudopolyps, hemorrhagic mucosa

10

wide superficial ulcers seen in ____; deep narrow ulcers seen in _____

UC; CD

11

fissures, fistulas, and fat wrapping are all seen in ____ because it is?

Crohn's; transmural

12

3 microscopic features that distinguish CD from UC

1. variable involvement, 2. transmural inflammation, 3. +/- granulomas

13

gross appearance of CD (6 things)

skip lesions, cobblestoning, linear ulcers, fissures, fistulas, fat wrapping

14

how do you diagnose IBD?

you must correlate biopsy findings WITH clinical hx and endoscopic findings (each alone is insufficient)