PATH2JEP Flashcards

(45 cards)

1
Q

antigen is

A

foreign body

micro-organisms and their toxins

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2
Q

name some antigens

A
tumor cells
cells infected with viruses
organ transplant 
tissue graft
incompatible blood transfusion 
cells of own body; autoimmune disease
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3
Q

what WBC is most prevalent in immune response

A

lymphocytes

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4
Q

types of lymphocytes

A

B cell
T cell
killer cells

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5
Q

where are T and B cell lymphocytes produced

A

stem cells in bone marrow

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6
Q

systemic lupus can have an oral or skin type lesion; shape

A

butterfly type

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7
Q

systemic lupus can have an oral or skin type lesion; what presentation for skin, texture

A

scaly lesion

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8
Q

systemic lupus can have an oral or skin type lesion; what presentation for skin, where?

A

nose and finger tips

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9
Q

what is a nikolsky sign in pemphigus vulgarism?

A

gentle friction a bulla can be produced

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10
Q

behcet syndrome needs 2 of 3 lesions to diagnose; what are the lesions

A

oral
genital
ocular

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11
Q

where do lymphocytes develop and mature

A

lymphoid tissue

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12
Q

what test that helps diagnose and evaluate disease

A

antibody titer; level of a specific anti-body

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13
Q

main function of T cell

A

increase function of the B-cell

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14
Q

what enzyme is created by the macrophages to help with phagocytosis

A

lysosomal enzymes

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15
Q

2 different types of immune response

A

humoral and cell mediated immunity

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16
Q

humoral is

A

antibody based

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17
Q

cell mediated is

A

T cell driven

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18
Q

2 types of immunity

A

passive

active

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19
Q

2 types of passive immunity

A

natural

acquired

20
Q

passive;natural meaning

A

through maternal source

21
Q

passive; acquired meaning

A

other sources immunization

22
Q

2 types of active immunity

A

natural

acquired

23
Q

active; natural meaning

A

exposure to micro-organisms building up anti-bodies

24
Q

active; acquired meaning

25
what is type 1 hypersensitivity in an immune reaction
immediate anaphylactic type reaction happens immediately
26
which type of drug ADMINISTRATION causes the most hypersensitivity reactions
topical | parenteral causes the most severe
27
what happens in an auto immune disease
- body can not distinguish self from non self - some body cells are not tolerated - treated as foreign
28
immunodeficiency DEF
``` deficiency in: number function interrelationship between WBC ```
29
most common cause of an aphthous ulcer
trauma
30
name other causes of an aphthous ulcer
``` stress hormonal tobacco cessation systemic diseases certain foods ```
31
3 types of aphthous ulcer
minor major herpetiform
32
what type of tissue do they occur
non-keratinized tissue
33
what is prodromal phase
where PT can "feel" something coming
34
how long do aphthous ulcers typically last
7-10 days
35
urticaria AKA
hives
36
angioedema AKA
swelling
37
urticaria and angioedema are typically caused by
allergy
38
urticaria and angioedema are cured by
benadryl/ antihistamine
39
dermatitis and mucositis are typically caused by
allergen contact on skin or mucosa
40
dermatitis and mucositis are typically cured by
topical or systemic corticosteroids
41
typical presentation of lichen planus
lace-like white patches that don't wipe off on the buccal mucosa
42
cause of lichen planus
unknown
43
what is the disease langerhans cell disease main appearance and age affected
skeletal brain radiolucent areas, affecting young children most often
44
the phenomena that occurs with sjogrens syndrome
raynauds phenomena
45
name some symptoms/ presentations of sjogrens
``` decreased blood flow pale tissue pain in joints arthritis type muscle pain fatigue ```