Pathogenesis and control of vira disease Flashcards Preview

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Flashcards in Pathogenesis and control of vira disease Deck (122)
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1

What are the 4 cellular responses to infection?

no effect, cytopathology, hyperplasia, cancer

2

(blank) are nuclear or cytoplasmic aggregates of stainable substances, usually viral proteins

inclusion bodies

3

Many viral infections are (blank)

subclinical

4

T or F
the same disease may be produced by a variety of viruses

T

5

T or F
the same disease may produce a variety of diseases

T

6

T or F
the disease produced bears no relationship to viral morphology

T

7

pathology is determined by what 3 factors?

viral factors
host factors
family genetics

8

What is the study of origin and development of disease?

pathogenesis

9

(blank) are events during infection that results in disease manifestation in the host

disease pathogenesis

10

A strain of virus is more (blank) than another strain if it commonly produces a more severe disease

virulent

11

What are the steps of viral pathogenesis?

viral entry into the host
primary site of viral replication
viral spread
cellular injury
host immune response
viral clearance or persistent infection
viral shedding

12

Is this a characteristic of local or systemic viral infections:
site of pathology is at portal of entry?

local

13

Is this a characteristic of local or systemic viral infections:
site of pathology is at distant site?

systemic

14

Is this a characteristic of local or systemic viral infections:
incubation period is relatively long?

systemic

15

Is this a characteristic of local or systemic viral infections:
incubation period is relatively short?

local

16

Is this a characteristic of local or systemic viral infections:
viremia is absent

local

17

Is this a characteristic of local or systemic viral infections:
viremia is present

distant

18

Is this a characteristic of local or systemic viral infections:
duration of immunity is variable (may be short)

local

19

Is this a characteristic of local or systemic viral infections: Duration of immunity is usually lifelong.

distant

20

Is this a characteristic of local or systemic viral infections:
role of secretory IgA in resistance is usually NOT important

distant

21

Is this a characteristic of local or systemic viral infections: role of secretory IgA in resistance is usually important

local

22

What are the ways that viruses attach and enter cells?

skin
respiratory tract
GI tract
urogenital tract

23

after primary site of entry, the virus may spread within the host. What is the most common route?

blood or lymphatics

24

What do you call presence of virus in the blood?

viremia

25

T or F
viruses may be free in the blood?

T
They may be free in the blood or associated with a specific cell type

26

What 2 viruses have neuronal spread?

HSV
rabies virus

27

viruses tend to exhibit organ and cell specificities, this is called (blank)

tropism

28

What does tropism determine?

the pattern of system illness produced

29

tissue and cell tropism relates to the presence of cell surface receptors that the viral (blank) bind to initiate entry

VAP (glycoproteins)

30

Why might a virus not produce viral proteins in a host cell?

due to lack of cellular transcription factor