Pathognomonic

Question 1

Auspitz sign

Answer 1

Psoriasis (pinpoint bleeding spots from exposure of dermal papillae when scales are scraped off)

Question 2

heliotrope rash

Answer 2

dermatomyositis

Question 3

anti jo 1

Answer 3

dermatomyositis and polymyositis

Question 4

Anti dna topoisomerase

Answer 4

Diffuse scleroderma

Question 5

Anti centromere

Answer 5

CREST

Question 6

anti citrullinated

Answer 6

Rheumatoid arthritis (citRUllinated)

Question 7

Schaumann and asteroid bodies

Answer 7

Sarcoid (Asteroid has sarcoid)

Question 8

Non caseating granuloma+ increased ACE

Answer 8

sarcoid

Question 9

Anti smooth muscle

Answer 9

autoimmune hepatitis

Question 10

Antihistone

Answer 10

Drug induced lupus

Question 11

dactylitis

Answer 11

psoriatic arthritis

Question 12

Assoc with temporal arteritis

Answer 12

polymyalgia rheumatica

Question 13

Monosodium urate crystals

Answer 13

gout

Question 14

calcium pyorphosphate crystals

Answer 14

pseudogout

Question 15

Tophus

Answer 15

gout

Question 16

Anti Ro

Answer 16

Sjogrens (also anti La) ribonucleoprotein

Question 17

Anti La

Answer 17

Sjogrens (also anti Ro) ribonucleoprotein

Question 18

Pannus

Answer 18

RA

Question 19

HLA DR4

Answer 19

RA

Question 20

Double bubble

Answer 20

Duodenal atresia or giant cell tumor of bone (epiphysis)

Question 21

Blue cell tumor

Answer 21

Ewings sarcoma

Question 22

Onion skin appearance in bone

Answer 22

Ewings sarcoma (also PSC and Tay sachs)

Question 23

Glistening mass in medullary cavity

Answer 23

chondrosarcoma

Question 24

Polyostotic fibrous dysplasia

Answer 24

(bone is replaced by fibroblast) think McCune Albright

Question 25

Verrucae

Answer 25

warts-- caused by hpv

Question 26

Plaques with silvery scaling

Answer 26

Psoriasis

Question 27

Multiple seborrheic keratoses (stuck on)

Answer 27

Indicates underyling malignancy

Question 28

Honey colored crusting

Answer 28

impetigo

Question 29

IgG AB against demoglein 3

Answer 29

pemphigus vulgaris

Question 30

IgG agst hemidesmisomes

Answer 30

bullous pemphigoid (antibodies are bullow the epidermis)

Question 31

christmas tree distribution rash

Answer 31

Pityriasis Rosea

Question 32

Colles fracture

Answer 32

Osteoporosis (can happen otherwise but very common in osteoporosis)

Question 33

Chalk stick fracture

Answer 33

Pagets disease

Question 34

Mosaic bone pattern

Answer 34

Pagets

Question 35

Sun burst appearance on xray

Answer 35

Osteosarcoma

Question 36

Pleimorphic cells that produce osteoid

Answer 36

Osteosarcoma

Question 37

Soap bubble appearance on x ray

Answer 37

Giant cell tumor of bone (epiphysis; knee region)

Question 38

Polished ivory appearance of bone

Answer 38

Osteoarthritis

Question 39

Bamboo spine

Answer 39

Ankylosing spondylitis

Question 40

Wichams striae

Answer 40

Lichen planus (reticular white lines on surface)

Question 41

Postauricular lymphadenopathy

Answer 41

Rubella (when speaking about child with rash)

Question 42

Cherry red appearance of skin?

Answer 42

CO poisoining

Question 43

String of pearls?

Answer 43

Polyarteritis nodosa; PCOS; small bowel obstruction

Question 44

Strawberry cervix?

Answer 44

Trichimonas

Question 45

Strawberry tongue?

Answer 45

Kawasaki, Toxic Shock Syndrome, Scarlet Fever

Question 46

p anca?

Answer 46

Microscopic polyangitis (no granulomas); Churg Strauss; ulcerative colitis

Question 47

Vasculitis with IgA deposition?

Answer 47

Henoch Shonlein Purpura

Question 48

Targetoid rash?

Answer 48

Erythema multiforme or Lyme disease

Question 49

Charcot leyden crystals?

Answer 49

Asthma-- eosinophilic breakdown in sputum

Question 50

Honey comb lung on xray?

Answer 50

Interstitial fibrosis

Question 51

Egg shell calcification?

Answer 51

Silicosis

Question 52

Ivory white calcified pleural plaque?

Answer 52

Asbestosis

Question 53

Chocolate agar blood and cyanosis?

Answer 53

Methemoglobin

Question 54

Golden brown fusiform rods--dumbbell shaped

Answer 54

Asbestos bodies (iron deposits)

Question 55

Hemosiderin laden macrophages?

Answer 55

Heart failure cells--macrophages consume blood-->build up of iron

Question 56

Nutmeg liver?

Answer 56

RHF

Question 57

Fixed splitting

Answer 57

ASD

Question 58

Boot shaped heart on xray?

Answer 58

TOF

Question 59

Hurthle cells

Answer 59

Hashimotos (also see lymphocytic infilitrates with germinal centers)

Question 60

Pretibial myxedema?

Answer 60

Hyperthyroidism

Question 61

Antimicrosomal antibody?

Answer 61

Hashimotos (also see antithyroglobulin)

Question 62

Antithyroglobulin antibody?

Answer 62

Hashimotos

Question 63

Dense core bodies

Answer 63

Carcinoid tumor

Question 64

Regenerative nodules and bridging fibrosis?

Answer 64

Cirrhosis