Pathology Flashcards

1
Q

functions of the skin

A
barrier
thermoregulation
fluid and electrolyte balance
endocrine (vitamin D)
protection from UV (melanin)
immunity
sensory functions
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2
Q

define hyperkeratosis

A

increased thickness of the keratin layer

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3
Q

parakeratosis

A

persistence of nuclei in the keratin layer

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4
Q

acanthosis

A

increased thickness of the epithelium

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5
Q

papillomatosis

A

irregular epithelial thickening

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6
Q

spongiosis

A

oedema between skin layers/keratinocytes

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7
Q

four classes of skin inflammatory diseases

A
  1. spongiotic-intraepidermal oedema
  2. psoriasiform-elongation of rete ridges
  3. lichenoid-basal layer damage
  4. vesiculobullous-blistering
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8
Q

example of spongiotic-intraepidermal oedema

A

eczema

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9
Q

example psoriasiform-elongation of rete ridges

A

psoriasis

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10
Q

examples of lichenoid-basal layer damage

A

lichen planus

SLE

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11
Q

examples of vesiculobullous-blistering

A

pemphigoid
pemphigus
dermatitis herpetiformis

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