Dermatology 2.0 > Pruritus > Flashcards

Pruritus Flashcards

(12 cards)

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1
Q

define

A

itch

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2
Q

mediators

A

chemicals
nerve transmission
CNS

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3
Q

chemical mediators

A 
histamine
PGE2
ACh
serotonin
kallikrein
IL-2
substance P
tryptase
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4
Q

nerve transmission

A

unmyelinated C fibres

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5
Q

CNS mediators

A

opiates

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6
Q

four types of pruritus

A

pruritoceptive
neuropathic
neurogenic
psychogenic

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7
Q

define pruritoceptive

A

usually assocaited with inflammation or dryness in skin that triggers itch

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8
Q

define neuropathic

A

damage to any of central or peripheral nerves causing itch

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9
Q

define neurogenic

A

no evident damage to CNS but itch caused by effects of opiates on CNS

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10
Q

define psychogenic

A

psychological cause with no pathology

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11
Q

management

A

determine cause

anti-itch treatment

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12
Q

anti-itch treatment

A 
antihistamines
emollients
antidepressants
phototherapy
opiate antagonists
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Dermatology 2.0
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