✅Pathology-INFECTIONS Flashcards Preview

PTHO > ✅Pathology-INFECTIONS > Flashcards

Flashcards in ✅Pathology-INFECTIONS Deck (109):
1

Most common presentation of mumps

Bilateral parotitis

2

Pathophysio of sterility in mumps

Caused by scars and atrophy of the testis after resolution of viral infection

3

Large pink to purple intranuclear inclusions found in herpes simplex infections

Cowdry type A bodies

4

Facial nerve paralysis in varicella

Ramsay hunt syndrome

5

Inclusions and morphology seen in CMV infection

Owl's eye inclusions- prominent intranuclear basophilic inclusions surrounded by halo

6

CMV vs EBV

Which is heterophile positive?

EBV

7

Which congenital infections can cause blueberry muffin baby?

CMV
Congenital rubella syndrome
Disemminated neuroblastoma

8

What is the drug of choice for CMV infection

Ganciclovir

9

Atypical lymphocytes found in EBV

Downey cells

10

What malignancies are associated with EBV?

Burkitt's lymphoma
Nasopharyngeal CA

11

Pathology in hidradenitis suppurativa

Apocrine sweat glands

12

Paronychia is an infection of the

Nail bed

13

Felon is an infection of the

Pulp

14

Scalded skin syndrome is also known as

Ritter disease

15

Toxin in s.aureus that cause scalded skin syndrome

Exfoliatin

16

Moa of exfoliatin in Ritter disease

Exfoliatin cleaves desmoglein in desmosones causing separation of epidermis at the stratum granulosum

17

Scalded skin syndrome vs TEN

Ritter - epidermis separation at stratum granulosum

TEN - dermis and epidermis

18

Other name for TEN

Lyell disease

19

Areas of friction in the axillary and ingunal area seen in scarlet fever

Pastia's lines

20

Diffuse edematous neutrophilic inflamattory reaction in the dermis and epid seen in S. pyogenes

Erysipelas

21

Toxin in scarlet fever seen in lysogenized strains

Erythrogenic toxin

22

Test determining susceptibility to scarlet fever

Dick test

23

Erysipelas vs malar rash

Erysipelas - painful

Malar rash - spares the nasal fold

24

Pseudomembranes in corynebacterium are made of

Necrosis of the epithelium with outpouring of a dense fibrinosuppurative exudate

25

Complications of corynebacterium diphtheriae

Airway obstruction
Myoarditis
Polyneuritis

26

Typical bacterial meningitis

Listeria monocytogenes

27

Morphology of listeria

Gram positive
intracellular
Bacilli

28

Describe the motility patter of the following:

Listeria
Proteus mirabilis
Vibrio cholerae
Giardia lamblia

Listeria - tumbling
Proteus mirabilis - swarming
Vibrio cholerae - shooting star
Giardia lamblia - falling leaf

29

None of the cephalosporins are effective against

Listeria
Enterococci
MRSA

30

Treatment for MRSA

Doxy
Co-tri
Clinda
Vanco

31

Bacillus anthracis morphology

Large boxcare shaped gram positive extracellular

32

Fatal complication of bacillus anthracis

Mediastinal hemorrhage

33

Modified acid fast stain for nocardia

Fite-faraco

34

Slender beaded gram positive arranged in braching filaments

Nocardia asteroided

35

Haze of bacilli entangled with the cilia of bronchial epithelia

Bordetella pertusis

36

Which virulence factor causes whooping in pertussis infection?

Tracheal cytotoxin

37

Pattern in necrotizing pneumonia in pseudomas aeruginosa

Fleur de lis pattern

38

Etiology of hot tub folliculitis

P. Aeruginosa

39

Etiology of ecthyma gangrenosum

P. aeruginosa

40

Lymph node enlargement in yersinia pestis

Buboes

41

Other plagues caused by yersinia pestis

Bubonic plague
Pneumonic plague
Septicemic plague

42

Painful genital ulcer

Chancroid

43

Etiology of chancroid cells

Haemophilus ducreyi

44

Beefy red ulcer with Pseudobuboes

Klebsiella granulomatis

45

Stain and findings for klebsiella granulomatis

Donovan bodies in warthin starry stain

46

Subpleural granuloma

Ghon's focus

47

Supleural granuloma + lymph node

Gohn's complex

48

Radiologically detectable calcifiction in TB

Ranke's complex

49

Focus found in apices in reactivation TB

Simon's focus

50

Most common site of intestinal tb

Ileum

51

Abundant acid fast bacilli within macrophages in patients with AIDS CD4

M. avium

52

Drives macrophages to contain TB in competent people

Gamma interferon

53

Mycobacterium leprae subtypes

Tuberculoid leprae
Lepromatous leprosy

54

Paucibacillary type of M. Leprae

Tuberculoid

55

Large aggregates of lipid laden macrophages in lepronatous leprosy

Lepra cells

56

Masses of acid fast bacilli in lepromatous leprae

Globi

57

Most common nerve involvement in lepromatous leprosy

Ulnar and peroneal nerves

58

Primary stage of syphilis

Chancre

59

Multinucleate giant cells found in measles

Warthin-finkledey cells

60

Secondary stage of syphilis

Palmar rash
Lymphadenopathy
Condyloma latum

61

Tertiary syphilis

Neurosyphillis
Aortitis
Gummas

62

Tabes dorsalis in syphillis is what stage?

Tertiary

63

Condyloma acuminata

HPV infection

64

Condyloma lata is found in

Syphilis (2nd stage)

65

Signs of congenital syphilis

Pneumonia alba
Hutchinson's teeth

66

Pale and airless lung in congenital syphilis

Pneumonia alba

67

What is hutchinson's teeth?

Small incisors shaped like a screwdriver or peg often with notches in enamel

68

Relapsing fever

Borrelia recurrentis

69

Clinical findings in borrelia recurrentis

Moderate splenomegaly
Erythrophagocytosis

70

Lyme disease

Borrelia burgdorferi

71

Acrodermatitis atrophicans is found in

3rd stage of lyme disease

72

CNS symptoms are found in what stage of lyme disease

2nd stage

73

Characterized by foul odor, gas bubbles, wide tissue destruction

Clostridum cellulitis

Clostridium perfringens

74

Irregularly shaped foci of necrosis in lymphogranuloma venereum

Stellate abscess

75

Chlamydia trachomatis are easy to gram stain and culture. T or F.

F

76

Basic pathophysiology in rickettsia

Vasculitis

77

2 ricketssial diseases

Typhus
Rocky mountain spotted fever

78

Focal microglial proliferations with an infiltrate of mixed T lymohocytes and macrophages in typhus fever

Typhus nodules

79

Hemmorhagic rash
Thrombosis of small blood vessels
Brain infarcts
Noncardiogenic pulmonary edema

Rocky mountain spotted fever

80

Morphology of cryptococcus neoformans

Thick gelatinous capsile and soap bubble lesions

81

Pathophysio of soap bubble lesions in cryptococcus neoformans

Yeasts grow in the meninges or expand the perivascular Virchow-Robin spaces

82

Acute angle of branching filaments

Aspergillus fumigatus

83

_____ lesions are seen in invasive aspergillosis

Target lesions

84

Right angle branching of filaments

Mucormycosis

85

Morphology of mucormycosis

Nonseptate, irregularly wide fungal hyphae with frequent RIGHT Angle branching

86

Systemic mycose

Spherules in endospores

Coccidiodes immitis

87

Systemic mycoses

Intracellular yeasts

Histoplasma capsulatum

88

Systemic mycosis

Board based bud

Blastomyces dermatitidis

89

Systemic mycoses

Mariner's wheel

Paracoccidiodes brasilensis

90

In malaria hepatosplenomegaly, black or gray parenchyma is due to

Hemozoin

91

Granulomas in cerebral malaria

Durck granulomas

92

Which microscopic dots are seen in the ff malarial species?

Vivax
Ovale
Malariae
Falciparum

Vivax - schuffner's dots
Ovale - schuffner's dots
Malariae - ziemann's dots
Falciparum- maurer's dots

93

What is the drug of choice for radical cure of benign tertian malaria?

Primaquine

94

Maltese cross pattern

Babesia microti

95

Black skin pigmentation in leishmaniasis

Kala-azar

96

T. Brucei

African sleeping sickness

97

Plasma cells containing cytoplasmic globules filled with Ig in african sleeping sickness

Mott cells

98

What characteristic sign of chagas disease is associated with unilateral periorbital edema

Romaña's sign

99

Other than myocarditis, what other expected complications in Chagas disease?

Megacolon
Megaesophagus

100

Rupture of hydatid cysts may lead to

Anaphylaxis

101

Parasite that encysts in striated muscle

Trichinella spiralis

102

The coiled larvae of trichinella spiralis is surrounded by menbrane bound vacuoles within

Nurse cells

103

Only carcinogenic parasite
What CA?

Schistosoma haematobium

SCCA of the bladder

104

Pattern of fibrosis in severe schistosomiasis

Pipe stem fibrosis

105

Characteristic lesions in mild schistosomiasis

White pinhead sized granulomas scattered throughout the gut and liver from regurgitated heme pigments

106

Dead microfilariae surrounded by stellate hyaline eosinophilic precipitates embedded in small epitheloid granulomas

Meyers kouvenaar bodies

107

Drug of choice for river blindness?

Ivermectin

108

River blindness is caused by

Onchocerca volvulus

109

What complications may arise during initiation of treatment due to lysis of onchocercal worms?

Mazzoti reaction