Pathology of chest malignancies Flashcards Preview

Year 2 Respiratory > Pathology of chest malignancies > Flashcards

Flashcards in Pathology of chest malignancies Deck (22)
1

what is the most common malignant lesion in the chest?

metastasis

2

what are the most common benign lesions in the chest?

granulomas
chronic pneumonia and abscess

3

which type of cancer makes up the vast majority of lung neoplasms?

carcinoma

4

what are the top 4 causes of pleural exudate?

microbes
cancer
pulmonary infarction
viral pleuritis

5

what are the diagnostic methods for diagnosing lung cancer?

sputum cytology
FNA
biopsy

6

hypercalcemia is more typically seen with what cancer type? the majority of the other paraneoplastic syndromes are seen with what type?

squamous cell CA

small cell

7

pancoast tumor is usually due to what cancer type?

squamous (can be adenoCA)

8

what are the histological classifications of lung tumors?

adenocarcinoma
squamous cell CA
small cell CA
large cell CA

9

what are the clinical classifications of lung tumors? what are they based on?

non small cell CAs
small cell CAs
combined patterns

response to chemo and likelihood of metastases

10

what are the mutations seen in adenocarcinomas?

KRAS and EGFR

11

KRAS and EGFR mutations are seen in what type of lung cancer?

adenocarcinoma

12

what are the two forms of adenocarcinoma?

bronchial
bronchioalveolar

13

what is the origin of bronchoalveolar CA?

bronchoalveolar stem cells

14

which lung cancer produces keratin?

squamous

15

which syndromes can result from squamous cell CA?

SVC
pancoast

16

what is the treatment of choice for SCLC?

chemo

17

which lung cancer is considered undifferentiated?

large cell CA

18

what is the most common metastasis site for primary lung cancer?

lymph nodes

19

what are tumorlets?

benign, small clusters of hyperplastic neuroendocrine cells

20

what is the benign pleural tumor?

pleural fibroma

21

what is the malignant pleural tumor?

mesothelioma

22

spindle cell tumor

solitary fibrous tumor (pleural fibroma)