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Year 2 Respiratory > COPD > Flashcards

Flashcards in COPD Deck (12)
1

definition: COPD

airflow limitation that is progressive and not fully reversible, associated with an abnormal inflammatory response to noxious particles or gases

2

what are the mechanisms of small airway limitation in COPD?

inflammation
fibrosis, luminal plugs
increased airway resistance

3

what are the mechanisms of parenchymal destruction in COPD?

loss of alveolar attachments
decrease of elastic recoil

4

definition: chronic bronchitis

cough that occurs every day with sputum production that lasts for at least 3 months, two years in a row

5

what therapy confers benefit in a1AT deficiency?

augmentation therapy

6

what are the steps for assessment of COPD?

1. assess symptoms
2. assess degree of airflow limitation using spirometry
3. assess risk of exacerbations
4. assess comorbidities

7

what is used to risk stratify patients for COPD?

modified medical research council questionnaire

8

what is the single most important intervention to prevent disease and slow progression of COPD?

smoking cessation

9

what is the anticholinergic short acting bronchodilator?

ipatropium bromide

10

when are inhaled corticosteroids indicated?

GOLD stage III or IV with significant symptoms or recurent exacerbations

11

what is the only therapy that improves survival in hypoxemic COPD?

oxygen

12

when should patients with COPD be given abx?

three cardinal symptoms (increased dyspnea, increased sputum volume, increased sputum purulence)

mechanical ventilation