Flashcards in Asthma Deck (18)
asthma cardinal symptoms
asthma risk factors
indoor allergen exposures
active or passive smoke exposure
what types of medications are associated with asthma?
beta blockers (non selective)
what is the common denominator and primary physiologic finding in asthma?
what is the cause of airway obstruction in asthma? the degree of severity depends on what?
inflammation and cellular infiltration
degree of bronchial hyperresponsiveness
the inflammation seen in asthma has what three identifiable components?
1. infiltration of airway with eosinophils and lymphocytes
2. upregulation of normal cells to proinflammatory state
3. alterations in non cellular components of airway wall
what are the four main inflammatory mediators of asthma pathogenesis?
platelet activation factor
what are the four components of airway obstruction?
smooth muscle contraction and hypertrophy
mucus gland hypersecretion and mucus plugging
are infection related asthma attacks usually bacterial or viral?
what are the specific diagnostic tests indicating asthma?
pre and post bronchodilator spirometry
serial peak flow measurements
what are the pitfalls of provocation testing?
false positive may follow recent infection
false negative may occur if patient is tested while on medication
presence of bronchial hyperreactivity alone is NOT diagnostic of asthma
what is the relationship of asthma and bronchial hyperreactivity?
everyone with asthma has bronchial hyperreactivity, but not everyone with bronchial hyperreactivity has asthma
what are the criteria for classification of asthma severity?
days with symptoms
peak flow rates
peak expiratory flow rate variability
what is the treatment for patients with intermittent asthma only (less than 2 episodes weekly)?
PRN rapid acting beta agonist only
COPD patients are typically treated with what medication class?
what medication should NEVER be used as a monotherapy for asthma?
long acting beta agonists
if a patient has more than intermittent asthma what must be added to the treatment regimen?