Pathology - Pathology of GERR Flashcards

1
Q

chloride is usually very low in vomiting .what other element does chloride track on a U and E profile

a.sodium
b.potassium
c.calcium
d.iodine

A

a.sodium

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2
Q

what is most of the CO2 in the body stored as

a.bicarbonate
b.carbonic acid
c.co2

A

a.bicarbonate mops up H+
if abnormal acid base abnormailty may be present

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3
Q

a low level of co2 usually indicates a…

a.metabolic alkilosis
b.metabolic acidosis

A

b.metabolic acidosis

most co2 stored as bicarbonate which mops up h+
if low amount it is overwhelmed and H+ builds up

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4
Q

which of these substances on the U and e profile is the end point of protein metabolism

a.urea
b.creatinine

A

a.urea

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5
Q

In Gi bleeding, dehydration and kidney failure which substance is expected to be raised on the U and E profile

a.urea
b.creatinine
c.co2
d.chlroide

A

a.urea

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6
Q

which of these is a waste product of metabolism

a.urea
b.creatinine

A

b.creatinine

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7
Q

a large rise in what on a u and e profile may indicate acute kidney injury

a.urea
b.creatinine
c.co2
d.chlroide

A

b.creatinine

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8
Q

which of these from the u and e is used along with age, gender and ethnicity to calculate GFR

a.urea
b.creatinine
c.co2
d.chlroide

A

b.creatinine

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9
Q

which element is the biggest contributor to osmolarity

a.potassium
b.chloride
c.sodium
d.iron

A

c.sodium

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10
Q

where does water move in cases of acute hyponatraemia

a.from brain to blood
b.from blood to brain

A

b.from blood to brain

brain swells
EMERGENCY to get sodium back to nromal levels

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11
Q

what is the main cause of hypernatraemia

a.diabetes insipidus
b.diabetes mellitus
c.severe dehydration

A

c.severe dehydration

usually in elderly or disabled patients who cannot communicate their need for water

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12
Q

what are the 3 possible mechanisms of hypokalaemia

A

too little potassium in. - chronic malnutrition

shift from blood into cells - alkalosis, drugs eg salbutumol

too much out- hyperaldosteronism, diuretics, dirrhoea and vomiting

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13
Q

what are the 3 mechanisms of hyperkalaemia

A

too much potassium in - IV

shift from bllod to cells - acidosis , tissue damage

too little out - kidney failure, hypoaldosteronism , ARBs, ACEi , potassium sparing diuretics

MEDICAL EMERGENCY- heart function decrease

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14
Q

management of hyperkalaemia

A

protect heart - calcium salts
check blood sugar
give insulin (potassium taken into cells) and sugar
monitor hypoglycaemia and potassium

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15
Q

patient has high bilirubin LFT shows
high ALT and AST
normal ALP and GGT
what is the likely aetiology

a.hepatic

b.cholestatic

A

a.hepatic

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16
Q

patient has high bilirubin LFT shows
high ALP and GGT
normal ALT and AST
what is the likely aetiology

a.hepatic

b.cholestatic

A

b.cholestatic

17
Q

what is the best test for assessing a failing liver

a.AST
b.bilirubin
c.ALT
d.prothrombin time
e.c reactive protein

A

d.prothrombin time

18
Q

what tests are done for Gi pathologies

A

H pylori
acute pancreatitis - lipase , amylase
pancreatic insufficiency - faecal elastase
tumour markers - cea
coeliac disease - anti transglutimase antibody

19
Q

what tests are done for endocrine pathologies

A

adrenal - cortisol, acth
thyroid, t3,t4,tsh
etc

beware of time of sample

dynamic tests eg stimulation and surpression