Pelvic Mass Flashcards

(44 cards)

1
Q

What are the non-gynaecological causes of a pelvic mass?

A

Bowel- constipation, caecal carcinoma, appendix abscess, diverticular abscess
Bladder/urological- urinary retention, pelvic kidney
Other- retroperitoneal tumour

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2
Q

What are the gynaecological locations of a pelvic mass?

A

Uterine- body, cervix
Tubal (& para-tubal)
Ovarian

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3
Q

What are the gynaecological causes of a uterine mass?

A

Pregnancy
Commonest fibroids
Endometrial cancer- early presentation (PMB), therefore mass unusual
Cervical cancer- also late mass presentation +- renal failure/bleeding/pain

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4
Q

Describe uterine fibroids

A

Very common, especially >40yo

Usually few cm, but may be bigger + multiple

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5
Q

What are some possible locations/classes of fibroids?

A
Pedunculated
Intracavitary
Intramural
Subserous
Submucous
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6
Q

How may uterine fibroids present?

A
May be asymptomatic/incidental finding
Menhorrhagia
Pelvic mass
Pain/tenderness (Only disproportionate if red generation e.g. pregnancy, menopause)
Pressure symptoms
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7
Q

What Ix should be carried out in suspected fibroids?

A

Hb if heavy bleeding
US usually diagnostic- smooth echogenic mass (often multiple)
MRI for more precise localisation

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8
Q

How are fibroids treated?

A

Expectant if asymptomatic
Otherwise hysterectomy if family complete
Alternatives- myomectomy, uterine artery embolisation, hysteroscopic resection

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9
Q

What may cause tubal swellings?

A

Ectopic pregnancy- may detect adnexal mass on US
Hydrosalpinx- often longstanding/incidental
Pyosalpinx- acute/inflammatory
Paratubal cysts (small/incidental)

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10
Q

Describe functional ovarian cysts

A

Related to ovulation- follicular and luteal cysts
Rarely >5cm diameter
Usually resolve spontaneously
Often asymptomatic/incidental
Expectant management appropriate
May be menstrual disturbance, bleed, rupture and cause pain

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11
Q

What can cause endometriotic cysts?

A

Endometriosis

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12
Q

What are endometriotic cysts associated with?

A

Severe dysmenhorrhoea
Premenstrual pain
Dyspareunia
Subfertility

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13
Q

Describe an endometriotic cyst(s)

A

Typically tender mass with nodularity and tenderness behind uterus
Occasional asymptomatic until large chocolate cyst, may rupture

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14
Q

Describe primary ovarian tumours arising from surface epithelium

A

Serous, mucinous, endometrioid, clear cell, Brenner

If benign cystadenoma, malignant cystadenocarcinoma

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15
Q

Describe primary ovarian tumours arising from germ cells

A

Benign cystic teratoma (dermoid cyst, common)

Malignant germ cell tumours (rare)

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16
Q

Describe primary ovarian tumours arising from stroma

A

If from granulosa cell may secrete oestrogens
If theca/leydig cell may secrete androgens
Also fibroma (beware Meig’s syndrome)

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17
Q

What are rare stigmata of dermoid ovarian cyst?

A

Totipotential
Teeth, sebaceous material, hair
Thyroid tissue-> thyrotoxicosis

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18
Q

What are rare stigmata of granulosa cell ovarian tumours?

A

May produce oestrogens leading to precocious puberty, PMB

19
Q

What are rare stigmata of thecal tumours?

A

May produce androgens, leading to hirsutism and virilisation

20
Q

What are rare stigmata of ovarian fibromas?

A

Meig’s syndrome benign fibroma but pleural effusion

21
Q

Where do 2’ ovarian tumours commonly come from?

A

Breast
Pancreas
Stomach
GIT

22
Q

How will ovarian cancer usually present?

A

May be mass, swelling, pressure symptoms
But if early transperitoneal spread- deposits on all peritoneal surfaces, omental disease/infiltration/malignant ascites with protein exudate

23
Q

What are the clinical features of ovarian cancer with early transperitoneal spread?

A

Deposits on all peritoneal surfaces
Omental disease/infiltration
Malignant ascites with protein exudate
Usually more insidious symptoms

24
Q

How can the presentation of ovarian cancer vary?

A
Heartburn/indigestion
Early satiety
Weight loss/anorexia.
Bloating 
‘Pressure’ symptoms (esp bladder)
Change of bowel habit
SOB/ Pleural effusion
Leg oedema  or DVT
25
What genes lead to a predisposition of breast and ovarian cancer?
BRCA1 & 2
26
What % of ovarian cancers have a genetic basis?
5%
27
What does HNPCC predispose to?
Bowel, endometrial, ovarian cancer and others
28
What are the RFs for ovarian cancer?
Age (old>young) Nulliparity FHx (OCP protective)
29
What tumour markers should be looked for in suspected ovarian cancer?
CA 125 | Carcino-embryonic antigen CEA
30
What imaging should be used Ix of suspected ovarian cancer?
US better for nature of cyst | CT better for assessing disease outwith ovary, especially omental and peritoneal disease, and LNs
31
In how many ovarian cancers is CA 125 raised?
~80%
32
What is a moderate raise of CA 125 associated with?
``` Endometriosis Peritonitis/infection pregnancy Pancreatitis Ascites from any cause e.g. liver disease Other malignancies gynae/non gynae ```
33
In what specific type of ovarian cancer is CEA often moderately elevated in?
Mucinous tumours
34
What is the main function of CEA testing?
Exclude mets from GI primary
35
What US findings should make you suspicious of ovarian cancer?
``` Complex mass with solid & cystic area Multi-loculated Thick septations Associated ascites Bilateral disease ```
36
What is the risk of malignancy index?
Menopausal status x CA 125 x US score
37
How are ovarian cysts/mass treated?
Removal or drainage if likely benign Other ovary/uterus removal with removal/biopsy of omentum Debulking of tumour and inspection of all peritoneal surfaces Chemo pre/post surgery
38
What cyst 'accidents' can present as an emergency?
Rupture Haemorrhage (into cyst) Torsion
39
How may fibroid degeneration present as an emergency with acute abdomen?
Usually red degeneration Compromised blood supply Seen in pregnancy, peri-menopause
40
What Ix should be carried out in pelvic mass?
``` Hb WCC/CRP if suspect inflammatory mass Biochemistry esp serum albumin Tumour markers (CA125, CEA, HCG,AFP) (CXR) Ultrasound TA/TV ```
41
What specific imaging could be carried out for fibroids/uterine mass?
MRI
42
What specific imaging could be carried out for suspected ovarian cancer?
CT
43
Is tissue aspiration for cytology helpful in pelvic mass investigation?
No
44
What imaging could be used in a guided tissue biopsy for pelvic mass?
CT/US