Pharm 1 - Exam 1: Cardio/Resp Flashcards Preview

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Flashcards in Pharm 1 - Exam 1: Cardio/Resp Deck (85)
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1

What is an non-selective adrenergic agonist used in the treatment of asthma?

Epinephrine
B-2 agonist

2

What form of administration is ineffective for Epinephrine?

oral

3

Name the long-acting beta 2 adrenergic agonist for asthma.

Salmeterol/Serevent

4

Which asthma drug must be used in conjunction with other therapies?

Salmeterol

5

What inhibits Salmeterol?

beta blockers

6

What is the class of drugs Ipratropium/Atrovent is in?

anticholinergics

7

Which asthma medication has the narrowest TI and in which class is it?

Theophylline/Theo-dur
xanthine/methylthanthine bronchodilator
*looks like caffiene

8

If you want to give an inhaled corticosteroid to an asthma patient, what med would you use?

Beclomethasone

9

If you have a patient with COPD or worsening asthma, what corticosteroid would you give?

Prednisone

10

Name a leukotriene inhibitor used in the treatment of chronic asthma. What enzymes does this drug inhibit?

Zafirlukast/Accolate
CYP450

11

What other class of drugs is often added to antitussives used in COPD?

Antihistamines

12

Name two antitussives and their classes given for COPD.

Codeine (narcotic analgesic/cough suppressant)
Dextromethorphan/DM (synthetic derivative of morphine/cough suppressant)

13

What is the MOA and #1 side effect for Diphenhydramine/Benadryl?

Histamine 1 receptor site blockage
sedation

14

Which drug is a non-sedating antihistamine used for allergic rhinitis? Why is it non-sedating?

Loratadine/Claratin
Don't cross BBB

15

T/F. Both Dephenhydramine and Loratadine block the production of histamine.

False. The receptor is just blocked.

16

Which drug would you choose if you wanted a nasal corticosteroid for treating nasal rhinitis?

Beclomethasone/Beconase

17

What is the most addictive OTC drug and its class? Hint: it's used to treat allergic rhinitis.

Phenylephrine/Afrin

18

This drug has the rebound effects of rhinitis medicosum

Phenylephrine/Afrin

19

What is the most effective smoking cessation drug and its MOA?

Varencycline/Chantix
partial agonist of alpha4/beta2 nicotinic acetylcholine receptor sites

20

What is the second most effective smoking cessation drug? What is it's MOA?

Bupriopion SR/Wellbutrin
dopamine-NE reuptake inhibitor (depression med)

21

What drug is based on the Ayurvedic herb Khella?

Cromolyn

22

What stage of HTN is a BP of 160-179/100?

Stage 2

23

What stage of HTN is a BP of 140-159/90s?

Stage 1

24

What Stage of HTN is a BP of >180/>110?

Stage 3/malignant HTN

25

Which HTN med is contraindicated in patients with low GFR and gout patients?

Hydrochlorthiazide/Hydrodiuril

26

Is Hydrochlorthiazide/Hydrodiuril K+ sparing or wasting?

wasting

27

Which two drugs help the K+ wasting of Hydrochlorthiazide/Hydrodiuril?

ACE inhibitors
B-blockers

28

Which class of drugs has the strongest diuretic effect?

loop diuretics

29

Name a loop diuretic. Is it safe to use in patients with renal failure?

Furosemide/Lasix
No, it's not effective for pts with renal failure but it is the drug of choice for those with low GFR or in hypertensive emergencies

30

What are the MC side effects of diuretics?

hypotension
edema