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Flashcards in Pharm 1 - Exam 2 Deck (94)
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1

This class of anti-arrhythmics contain beta blockers.

Class II

2

Class III Anti-arrhythmics affect what channel?

K+ Channel

3

This class of Anti-arrhythmics affects Ca+ channels.

Class IV

4

This drug is a Class Ia anti-arrhythmic that affects phase 0 of the cardiac cycle

Quinidine/Quinidex

5

Describe the presentation of cinchonism (5 things)

1. blurred vision
2.n/v
3. tinnitus
4. HA
5. disorientation/psychosis

6

This drug may induce ventricular tachycardia, called Torsades des Pointes

Quinidine/Quinidex

7

Name the cardiac specific beta blocker and its class that is indicated for arrythmias.

Atenolol/Tenormin
Class II Anti-arrhythmic

8

What phase of cardiac AP do Class II and Class IV anti-arrythmics affect? What side effect might they both have?

phase 4
bradycardia because they slows AV conduction

9

What is the most common side effect of all anti-arrythmics?

another arrhythmia

10

In what class of drugs is Amiodarone/Cordarone?

Class III Anti-arrhythmic

11

This drug has the potential to produce a blue-grey coloring of the skin due to it's high iodine content.

Amiodarone/Cordarone
ami-IOD-arone = iodine

12

In what anti-arrhythmic class is Verapamil?

Class IV
Ca+ Channel Blocker

13

Name three "other" anti-arrhythmics

Adenosine/Adenocard
Atropine
Digoxin/Lanoxin

14

This is the official drug of choice for the initial treatment of PSVT (paroxysmal superventricular tachycardia)

Adenosine/Adenocard

15

Adenosine/Adenocard has a duration of action of ___________.

~15 seconds

16

This drug is indicated (for cardiac use) in life threatening bradycardia and hypotension

Atropine

17

What is the MOA of Atropine?

Anti-cholinergic/parasympolytic
Competitive inhibitor of muscarinic ACh receptors

18

Name 4 extra-cardiac uses of Atropine

1. diarrhea
2. pre-operative (decreases bronchial & salivary secretions)
3. to treat organophosphate poisoning
4. as a cycloplegic/mydriatic (paralyzes accomodation/dilates pupils)

19

What does SLUDGE stand for and what does it indicate?

Salivation
Lacrimation
Urination
Diarrhea
Gastric Distress
Emesis
ORGANOPHOSPHATE POISONING

20

What type of toxicity is described by saying: "Dry as a bone, red as a beet, hot as a hare and mad as a hatter"?

Atropine

21

What is the antidote for Atropine?

physostigmine

22

Digoxin toxicity potential is increased when combine with what other drug class?

K+ wasting drug without K+ supplementation

23

The long half-life of Digoxin may have what effect on an EKG reading?

Flattening or inversion of the T wave

24

What 4 systems are affected in Digitalis intoxication?

Cardiac (arrhythmias/bradycardia)
CNS
GI
Vision

25

What is the antidote for Digoxin?

Digoxin immune Fabs

26

What number should LDL/HDL not exceed?

2.5

27

Total Cholesterol/HDL should not exceed ___

4

28

Niacin causes what characteristic side effects?

flushing
pruritus
myositis
GI issues

29

What lab values should be watched with Niacin/Nicotinic Acid use?

Liver enzymes

30

In what patients is Niacin contraindicated?

Poorly controlled DM
Active Liver Dz
Active PUD