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Flashcards in Pharm 1 - Exam 3 Deck (78)
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1

Which three anti-fungals target ergosterol in the cell membrane of fungi and protozoa?

Clotrimazole/Lotrimin
Nystatin/Mycostatin
Amphotericin B/Amphocil

2

Name two topical anti-fungals that could be used to treat tinea and other superficial skin infections.

Clotrimazole/Lotrimin
Terbinafine/Lamisil

3

What class of drugs often has an -azole ending?

anti-fungals

4

What is the current drug of choice for the treatment of onychomycosis of toenail or fingernail?

Terbinafine/Lamisil

5

What labs should be monitored when using Terbinafine/Lamisil orally?

Liver fx

6

This is the drug of choice for yeast infections, systemic mycoses, cryptococcous, and histoplasmosis.

Fluconazole/Diflucan

7

This drug has side effects that may be improved by pre-medication treatment with NSAIDs, prednisone or benedryl.

Amphotericin B/Amphocil

8

This drug is often reserved for severe systemic fungal infections because of its "shake and bake" side effects.

Amphotericin B/Amphocil AKA Ampho-terrible

9

What is the drug combination used to treat tuberculosis?

RIPE:
Rifampin
Isoniazid (INH)/Nitrazid
Pyrazinamide
Ethambutol/Myambutol

10

Which drug, used to treat tuberculosis, inhibits the synthesis of mycolic acid in the cell wall and is known for causing paresthesias?

INH/Nitrazid

11

This drug, used to treat TB, is known to induce pyridoxine deficiency and therefore B6 must be a part of the protocol.

INH/Nitrazid

12

This drug is used to treat Influenza A and B but must be given within 48 hours of the onset of symptoms?

Oseltamivir/Tamiflu (oral)

13

Which drug is given as an oral inhaler to treat influenza?

Zanamivir/Relenza

14

Which drug is used to treat influenza as well as Parkinson's disease (short-term)?

Amantadine/Symmetrel

15

What influenza drug is known to have bronchospasm as a side effect?

Zanamivir/Relenza

16

What is the MOA for the influenza drugs?

Inhibits neuramidase, which prevents viral budding

17

This drug is used to treat active herpes infection.

Acyclovir/Zovirax

18

This drug is a guanosine analog that is incorporated into the viral DNA - inhibits replication

Acyclovir/Zovirax

19

What are the 4 kinds of HIV drugs?

Reverse Transcriptase Inhibitors
Protease Inhibitors
Fusion Inhibitors
Integrase Inhibitors

20

What does HAART stand for?

Highly Active Antiretroviral Therapy

21

What makes up HAART treatment?

A combination of at least 3 HIV drugs

22

Name the reverse transcriptase drug.

Zidovudine (AZT)/Retrovir

23

Name the protease inhibitor drug.

Saquinavir/Invirase

24

This HIV drug is a pyrimidine analog.

Zidovudine (AZT)/Retrovir

25

What is alpha interferons used for?

Hep C

26

What are beta interferons used for?

Relapsing MS

27

What are gamma interferons used for?

Granulomatous disease

28

What is added to pegylated IFN alpha to make it last longer in the body?

polyethylene glycol

29

When treating Hep C, which drug often accompanies pegylated IFN alpha?

Ribavirin

30

Which 4 vaccines are killed virus?

Polio
Rabies
Hep A
Influenza (TIV/injected)