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Flashcards in Pharm general Deck (108)
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1

Acetaminophen o/d

N-acetylcysteine (replenishes glutathione)

2

AChE inhibitors, organophosphates o/d

Atropine followed by pralidoxime

3

Amphetamines (basic) o/d

NH4Cl (acidify urine)

4

Antimuscarinic, anticholinergic agents o/d

Physostigmine salicylate, control hyperthermia

5

Benzodiazepines o/d

Flumazenil

6

β-blockers o/d

Glucagon

7

Carbon monoxide o/d

100% O2, hyperbaric O2

8

Copper, arsenic, gold o/d

Penicillamine

9

Cyanide o/d

Nitrite + thiosulfate, hydroxocobalamin

10

Digitalis o/d

Anti-dig Fab fragments

11

Heparin o/d

Protamine sulfate

12

Iron o/d

Deferoxamine, deferasirox

13

Lead o/d

EDTA, dimercaprol, succimer, penicillamine

14

Mercury, arsenic, gold o/d

Dimercaprol (BAL), succimer

15

Methanol, ethylene glycol (antifreeze) o/d

Fomepizole > ethanol, dialysis

16

Methemoglobin o/d

Methylene blue, vitamin C

17

Opioids o/d

Naloxone

18

Salicylates o/d

NaHCO3 (alkalinize urine), dialysis

19

TCAs o/d

NaHCO3 (plasma alkalinization)

20

tPA, streptokinase, urokinase o/d

Aminocaproic acid

21

Warfarin o/d

Vitamin K, plasma (if active bleeding)

22

What Rx causes Coronary vasospasm

Cocaine, sumatriptan, ergot alkaloids

23

What Rx causes Cutaneous flushing

Vancomycin, Adenosine, Niacin, Ca2+ channel blockers

24

What Rx causes Dilated cardiomyopathy

Doxorubicin, daunorubicin

25

What Rx cause Torsades de pointes

Class III (e.g., sotalol) and class IA (e.g., quinidine) antiarrhythmics, macrolide antibiotics, antipsychotics, TCAs

26

What Rx cause Adrenocortical insufficiency

HPA suppression 2° to glucocorticoid withdrawal

27

What Rx cause Hot flashes

Tamoxifen, clomiphene

28

What Rx cause Hyperglycemia

Tacrolimus, Protease inhibitors, Niacin, HCTZ,
β-blockers, Corticosteroids

29

What Rx cause Hypothyroidism

Lithium, amiodarone, sulfonamides

30

What Rx cause Acute cholestatic hepatitis, jaundice

Erythromycin