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Flashcards in Pharm8 - Pharm8 Deck (50)
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1

which drugs cause pulmonary fibrosis?

busulfan bleomcyin amiodarone

2

which drugs cause gyneomastia

'Some drugs create awesome knockers' spironolactone digitalis cimetidine alcoholism ketoconazole (estrogen)

3

which drugs cause SLE like syndrome

'it's not HIPP to have lupus' hydralazine inh procainamide phenytoin

4

which drugs --> osteoporosis

CHO corticosteroids heparin

5

which drug --> gingival hyperplasia

phenytoin

6

which drugs --> photosensitivity

Amy played Tetris on her cell phone in the sun amiodarone sulfonamides tetracycline

7

which drugs --> tendonitis and tendon rupture in kids

fluoroquinolones

8

which drug --> gray baby syndrome

chloramphenicol

9

which drugs --> agranulocytosis

colchicine carbamazepine clozapine

10

which drugs --> atropine like side effects

tricyclics

11

which drugs --> cardiac toxicity

Dawn sat on the Docks mending her red, broken heart doxorubicin daunorubicin

12

which drugs --> torsades de pointes

Ia and III aniarrhytmics cisapride

13

which drugs --> focal/massive hepatic necrosis

Hello Val! Have a seat before your liver dies! halothane valproic acid acetaminophen

14

which drug --> fanconi's syndrome

expired tetracycline

15

which drug --> interstitial nephritis

methicillin

16

which drugs --> hemorrhagic cystitis

cyclophosphamide ifosfamide

17

which drug --> hepatitis

INH

18

which drugs --> pseudomembranous colitis

I have to take a CLAMP clindamycin ampicillin

19

which drugs --> nephrotoxicity AND ototoxicity

'if you call, i won't be able to hear you in the bathroom' Cisplatin aminoglycoside loop diuretics

20

which drugs --> seizures

buproprion imipenem clistatin

21

which drugs --> DI

lithium demeclocycline

22

which drugs --> aplastic anemia

chloramphenicol benzene NSAIDS

23

which drug --> coronary vasospasm

cocaine

24

which drugs --> flushing

AIDEN was in the VAN FLUSHING NIACIN and CALCIUM niacin CCB adenosine vancomycin

25

which drug --> hemolysis in G6PD pts

sulfonamides INH aspirin ibuprofen primaquine nitrofurantoin

26

whch drugs --> acute aholestatic hepatitis

macrolides

27

which drugs --> cinchonism

quinidine quinine

28

which drugs --> disulfiram like rxn

metronidazole some cephalosporins procarbazine sulfonylureas

29

which drug --> neurotoxicity/nephrotoxicty

polymyxins

30

uses for cytarabine

AML

31

examples of nitrosureas

'you MUST not let the Nitro go to your head, or you'll do a strip tease- a sin!' carmustine lmoustine semustine streptozacin

32

uses for nitrosureas

brain tumors (incl. GBM)

33

uses of the -platins

Platinum treated BOLTs breast ovarian lung testicular

34

uses for busulfan

'I will bustle to treat my dark CaMeL' CML

35

adverse effects of busulfan

'I will bustle to treat my DARK CaMeL' hyperpigmentation pulmonary fibrosis

36

uses for rubicins

'MS. Hodgkin's will LOB the RED ball' myeloma sarcoma Hodkin's lung ovarian breast

37

uses for dactinomycin

'children ACT out' rhabdomyosarcoma wilm's tumor ewing sarcoma

38

MOA 6MP

blocks do novo purine synth, activated by HGPRTase

39

which 2 drugs work synergistically with each other to prevent DNA replicaion?

5-FU MTX

40

MOA MTX

blocks DHF reductase, preventing DHF --> THF

41

MOA 5FU

blocks thymidylate synthase (preventing dUMP --> dTMP)

42

which cancer agen has minimal myelosuppression?

bleomycin

43

leucovorin

folinic acid that can reverse some of the myelosuppression associated with MTX (doesn't do anything for 5FU myelosuppression)

44

'rescue agent' for 5FU

thymidine

45

which cancer agent --> macrovesicular fatty change in liver?

MTX

46

cancer agents that alkylate DNA

Busulfan Platins Nitrosureas cyclophosphamide/ifosfamide

47

which alkylating agent requires bioactivation

nitrosureas

48

uses for -phosphamides

non-hodgkin's breast ovarian

49

which drugs intercalate in DNA?

3D doxorubicin daunorubicin dactinomycin

50

which cancer agents generate free radicals

doxorubicin daunorubicin bleomycin