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Flashcards in Pharmacology Deck (55):
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Allopurinol inhibits

Xanthine oxidase

1

Acute gout

Colchicine

2

Given in combination with Imipenem

Cilastatin

3

Drug for Parkinson's disease

Tacrine

4

Inhibitor of thromboxane A2

Aspirin

5

DOC for CML

Busulfan

SE: pulmonary fibrosis

6

Treatment for glaucoma

Pilocarpine

7

Carbonic anhydride used in glaucoma

Acetazolamide

8

MOA of Orlistat

Reversible inhibitor of lipase

9

Phosphate analogue to treat CMV

Foscarnet

10

Chemotherapeutic agent of choice in colon CA

5-FU
MOA: thymydilate synthase inhibitor

11

NSAID protective for colon CA

Aspirin

12

Gray baby syndrome

Chloramphenicol

Other SE: aplastic anemia

13

SE of tetracycline

Teeth discoloration
Epiphyseal plates
Milk alkali syndrome

14

Milk alkali syndrome

Antacids + Tetracycline

15

DOC for cholera

Tetracycline

16

DOC for leptospirosis

Doxycycline

Also used for Chlamydia

17

Red man syndrome

Vancomycin

18

Causes gingival hyperplasia

Chronic phenytoin toxicity

19

Anti-hypertensive contraindicated in pregnancy

ACE inhibitors

It causes fetal renal agenesis

20

SE of ACE inhibitors

Cough

Due to Bradykinin

21

SE: Ethambutol

Barrel-vision
Optic neuritis

22

Drug that causes peripheral neuropathy? Treatment?

INH
Treatment: Pyridoxine

23

Dissociative anesthetic

Ketamine

24

Malignant hyperthermia

Succinylcholine + Halothane

Succinylcholine is a neuromuscular blocker
DOC: Dantrolene

25

Twilight sleep

Sedative + Scopolamine

Scopolamine (anti cholinergic drug): used for motion sickness

26

DOC for vertigo

Beta-histine

27

Drugs used for motion sickness

Meclizine
Scopolamine

28

Chemodrug that causes cardiac toxicity

Doxurubicin

29

Hemorrhagic cystitis

Cyclophosphamide

30

DOC for Absence seizure

Ethosuximide

MOA: decrease calcium

31

Bronchodilator used to reduce uterine contractions in premature labor

Ritodrine

Others: Terbutaline

32

Pre-op drug to control thyrotoxicosis

Propanolol

Alternative: Lugol's iodine (to decrease vascularity and size of the gland)

33

Drug that penetrate the burn eschar

Mafenide acetate

34

Toxic metabolite of INH

Acetyl hydrazine

35

Asthma drug that has a narrow therapeutic index

Aminophyline
(Theophylline)

Has many drug interactions

36

DOC for vomiting in pregnancy

Hyperemesis gravidarum

Give Pyridoxine (vitamin B6)

37

Magnesium sulfate level where patellar reflex disappear

8

38

Role of magnesium sulfate in pre-eclampsia

Anti-convulsant

39

Antidote for organophosphate poisoning after 12 hours

Acute: Atropine
Chronic: Pralidoxime

40

DOC for post-chemo vomiting

Ondansetron

41

DOC for beta blocker overdose

Glucagon

42

Antidote for paracetamol toxicity

N-acetylcysteine

43

DOC for Tourette's syndrome

Haloperidol

44

MOA of coccaine

Inhibits diffusion and re-uptake via NET and DAT in synaptic cleft

NET: NE transport
DAT: Dopamine agonist transport

45

Mechanism of interaction in milk-alkali syndrome

Chelation

46

Preoperative anesthesia use of atropine

Decrease respiratory secretions

47

Why is atropine added to diphenoxylate

To prevent abuse

48

DOC for salmonella carrier

Ciprofloxacin

Reservoir for S. typhi: gallbladder

49

Somatren is a

GH analogue

50

DOC for extraluminal amoebiasis

Metronidazole

51

Luminal amoebacide

Diloxanide

52

DOC for diabetic gastroperesis

Metoclopramide

53

Anti thyroid drug for pregnancy

PTU

54

Second line anti-TB drug which is a structural analogue of INH

Ethionamide