Pharmacology Flashcards

0
Q

Acute gout

A

Colchicine

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1
Q

Allopurinol inhibits

A

Xanthine oxidase

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2
Q

Given in combination with Imipenem

A

Cilastatin

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3
Q

Drug for Parkinson’s disease

A

Tacrine

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4
Q

Inhibitor of thromboxane A2

A

Aspirin

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5
Q

DOC for CML

A

Busulfan

SE: pulmonary fibrosis

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6
Q

Treatment for glaucoma

A

Pilocarpine

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7
Q

Carbonic anhydride used in glaucoma

A

Acetazolamide

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8
Q

MOA of Orlistat

A

Reversible inhibitor of lipase

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9
Q

Phosphate analogue to treat CMV

A

Foscarnet

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10
Q

Chemotherapeutic agent of choice in colon CA

A

5-FU

MOA: thymydilate synthase inhibitor

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11
Q

NSAID protective for colon CA

A

Aspirin

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12
Q

Gray baby syndrome

A

Chloramphenicol

Other SE: aplastic anemia

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13
Q

SE of tetracycline

A

Teeth discoloration
Epiphyseal plates
Milk alkali syndrome

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14
Q

Milk alkali syndrome

A

Antacids + Tetracycline

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15
Q

DOC for cholera

A

Tetracycline

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16
Q

DOC for leptospirosis

A

Doxycycline

Also used for Chlamydia

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17
Q

Red man syndrome

A

Vancomycin

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18
Q

Causes gingival hyperplasia

A

Chronic phenytoin toxicity

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19
Q

Anti-hypertensive contraindicated in pregnancy

A

ACE inhibitors

It causes fetal renal agenesis

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20
Q

SE of ACE inhibitors

A

Cough

Due to Bradykinin

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21
Q

SE: Ethambutol

A

Barrel-vision

Optic neuritis

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22
Q

Drug that causes peripheral neuropathy? Treatment?

A

INH

Treatment: Pyridoxine

23
Q

Dissociative anesthetic

24
Malignant hyperthermia
Succinylcholine + Halothane Succinylcholine is a neuromuscular blocker DOC: Dantrolene
25
Twilight sleep
Sedative + Scopolamine Scopolamine (anti cholinergic drug): used for motion sickness
26
DOC for vertigo
Beta-histine
27
Drugs used for motion sickness
Meclizine | Scopolamine
28
Chemodrug that causes cardiac toxicity
Doxurubicin
29
Hemorrhagic cystitis
Cyclophosphamide
30
DOC for Absence seizure
Ethosuximide MOA: decrease calcium
31
Bronchodilator used to reduce uterine contractions in premature labor
Ritodrine Others: Terbutaline
32
Pre-op drug to control thyrotoxicosis
Propanolol Alternative: Lugol's iodine (to decrease vascularity and size of the gland)
33
Drug that penetrate the burn eschar
Mafenide acetate
34
Toxic metabolite of INH
Acetyl hydrazine
35
Asthma drug that has a narrow therapeutic index
Aminophyline (Theophylline) Has many drug interactions
36
DOC for vomiting in pregnancy
Hyperemesis gravidarum Give Pyridoxine (vitamin B6)
37
Magnesium sulfate level where patellar reflex disappear
8
38
Role of magnesium sulfate in pre-eclampsia
Anti-convulsant
39
Antidote for organophosphate poisoning after 12 hours
Acute: Atropine Chronic: Pralidoxime
40
DOC for post-chemo vomiting
Ondansetron
41
DOC for beta blocker overdose
Glucagon
42
Antidote for paracetamol toxicity
N-acetylcysteine
43
DOC for Tourette's syndrome
Haloperidol
44
MOA of coccaine
Inhibits diffusion and re-uptake via NET and DAT in synaptic cleft NET: NE transport DAT: Dopamine agonist transport
45
Mechanism of interaction in milk-alkali syndrome
Chelation
46
Preoperative anesthesia use of atropine
Decrease respiratory secretions
47
Why is atropine added to diphenoxylate
To prevent abuse
48
DOC for salmonella carrier
Ciprofloxacin Reservoir for S. typhi: gallbladder
49
Somatren is a
GH analogue
50
DOC for extraluminal amoebiasis
Metronidazole
51
Luminal amoebacide
Diloxanide
52
DOC for diabetic gastroperesis
Metoclopramide
53
Anti thyroid drug for pregnancy
PTU
54
Second line anti-TB drug which is a structural analogue of INH
Ethionamide