Physio of Auditory & Vestibular System Flashcards Preview

NeuroEndo Test 3 > Physio of Auditory & Vestibular System > Flashcards

Flashcards in Physio of Auditory & Vestibular System Deck (64)
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1

The basilar membrane is _____ and _____ near the oval and round windows.

narrow and stiff

2

The basilar membrane is _____ and _____ near the helicotrema.

wide and flexible

3

High frequency sounds deflect at the _____ part of the basilar membrane.

base/oval window

4

Low frequency sounds deflect at the _____ part of the basilar membrane.

apex/helicotrema

5

____ is where distinct locations of the basilar membrane interpret discrete frequencies. This is analogous to ____.

Tonotopy; somatotopy

6

The vibration of the basilar membrane creates a _____ ______ of the cochlea.

pressure differential

7

The pressure differential of the cochlea results in a ______ ______ against the stationary tectorial membrane.

shearing force

8

The shearing force of the tectorial membrane causes displacement of the .......

stereocilia of the outer hair cells.

9

The inner hair cells are activated by .......

fluid movement in the cochlear duct.

10

Depolarization of the cell occurs when _____ _____ open at the apex of the stereocilia.

cation channels

11

Stereocilia are connected to each other via tip links that transmit force to an elastic gating spring, which, in turn, opens the ____ ____.

TRPA1 channels

12

TRPA1 channels are _______ channels.

mechanotransduction

13

Endolymph is potassium-____.

RICH

14

Endolymph fills the ____ ____ and _____ _____.

cochlear duct and membranous labyrinth

15

Endolymph bathes the ......

apical end of the hair cells.

16

Endolymph is found in the ____ ____.

scala media

17

Endolymph is made by the _____ _____.

stria vascularis

18

Perilymph is potassium-____.

POOR

19

Perilymph bathes the ........

basal end of the cochlear hair cells.

20

Perilymph is found in the ____ ____ and ____ ____.

scala vestibuli and scala tympani

21

The opening of cation channels on stereocilia will cause a rapid influx of ___ into the cell.

K+

22

Influx of K+ into the hair cell causes ____ of the cell.

depolarization

23

Depolarization of the hair cells causes ____ channels at the base of the cells to open.

Ca++

24

Calcium influx into the hair cell causes which neurotransmitter to be released into the synaptic cleft?

Glutamate

25

What does glutamate being released into the synaptic cleft cause?

Stimulation of the afferent cochlear nerve fibers and transmission of a signal to the CNS (sending info to the tracts).

26

An upward displacement of the basilar membrane creates a shearing force that results in _____ _____ of the stereocilia.

lateral displacement

27

Lateral displacement of the stereocilia causes _____ of the hair cell.

depolarization

28

A downward displacement of the basilar membrane creates a shearing force that results in ______ of the hair cell.

hyperpolarization

29

The high endocochlear potential (+80 mV) serves to drive positively charged ions into the hair cell ___ their concentration gradient.

down

30

The endocochlear potential forms the ____ ____.

blood-labyrinth barrier (BLB)