PRELIM 05 - Evaluation of Drugs and Extraction

Question 1

Means “impression on the organs”; evaluation by means of the sense organs (Evaluation of drugs)

Answer 1

Organoleptic

Question 2

Involves the use of microscope to evaluate detailed examination of crude drugs in the entire and powdered forms (Evaluation of drugs)

Answer 2

Microscopic evaluation

Question 3

Determination of various physical characteristics using various physicochemical techniques (Evaluation of drugs)

Answer 3

Physical evaluation

Question 4

Used in determining the pharmacological activity of the drug (Evaluation of drugs)

Answer 4

Biologic evaluation

Question 5

Biologic evaluation is also known as __________ or __________ (BB)

Answer 5

Biological assay, Bioassay

Question 6

Pigeon (Drug assayed)

Answer 6

Digoxin

Question 7

Cat (Drug assayed)

Answer 7

Atropine

Question 8

Rabbit (Drug assayed)

Answer 8

Insulin

Question 9

Sheep plasma (Drug assayed)

Answer 9

Heparin

Question 10

Consists of both qualitative and quantitative tests used in determining the active constituent present (Evaluation of drugs)

Answer 10

Chemical evaluation

Question 11

Chemical tests that include identification tests for various phytoconstituents

Answer 11

Qualitative chemical tests

Question 12

Chemical tests used for determining the amount of chemical in a sample

Answer 12

Quantitative chemical test

Question 13

Test used for determining the presence of starch

Answer 13

Iodine test

Question 14

Test used for determining caffeine and other purine derivatives

Answer 14

Murexide test

Question 15

Are vegetable and animal drugs that consist of natural substances that have undergone only the processes of collection and drying

Answer 15

Crude drug

Question 16

Refers to the chief constituent obtained after extraction

Answer 16

Derivatives/Extractives

Question 17

Refers to the solvent used for extraction

Answer 17

Menstruum

Question 18

Refers to the undissolved portion of the drug that remains after the extraction process is completed

Answer 18

Marc

Question 19

Refers to plants growing in their native countries

Answer 19

Indigenous

Question 20

__________ is indigenous to the Southern US

Answer 20

Pinus palaustris

Question 21

__________ is indigenous in the mountainous regions of Europe

Answer 21

Aconitum napellus

Question 22

Refers to plants grown in a foreign land or in a locality other than their native homes

Answer 22

Naturalized

Question 23

__________ is a naturalized plant which was introduced into the US from Europe

Answer 23

Datura stramonium

Question 24

The process of separating a substance or constituent from a matrix which is usually derived from a natural source

Answer 24

Extraction

Question 25

The main product of extraction is called __________

Answer 25

Extractives

Question 26

The properly comminuted drug is permitted to soak in the menstruum (Types of extraction)

Answer 26

Maceration

Question 27

Latin word which means "to soak"

Answer 27

Macerare

Question 28

Refers to the material left after extraction in maceration

Answer 28

Marc

Question 29

Refers to the solvent used in maceration

Answer 29

Menstruum

Question 30

Process in which the constituents of a comminuted drug is extracted by the slow passage of a suitable column of drug (Types of extraction)

Answer 30

Percolation

Question 31

Latin word which means "through"

Answer 31

Per

Question 32

Latin word which means "to strain"

Answer 32

Colare

Question 33

A special type of column used in percolation

Answer 33

Percolator

Question 34

Refers to the collected material after percolation

Answer 34

Percolate

Question 35

Refers to extraction with the aid of gentle heat (Types of extraction)

Answer 35

Digestion

Question 36

In digestion, the mixture is placed in a water bath or in an oven at a temperature of about __________°C

Answer 36

50°C

Question 37

Extraction that involves boiling of the material in water for 15 minutes (Types of extraction)

Answer 37

Decoction

Question 38

Uses a Soxhlet extractor; a dried, grinded, and finely powdered plant material is placed inside a porous bag made up of a clean cloth or strong filter paper (Types of extraction)

Answer 38

Soxhlet extraction

Question 39

Soxhlet extraction is also known as __________

Answer 39

Continuous hot extraction