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Flashcards in Prescribing in liver disease Deck (5):
1

Give examples of two substances which undergo saturable kinetics?

Phenytoin
Alcohol

2

What sex hormones are not metabolised well with cirrhosis?

Aldosterone and estrogen

3

What are the consequences for the kidney in cirrhosis?

Potassium loss (hypokalaemic)
Sodium retention
Water retention

4

What causes hepato-renal syndrome?

Aldosterone and endothelin causing renal vasoconstriction

5

What are the consequences of moderate hepatic impairment?

Gut oedema
-poor absorption
Liver & kidney congestion
-Reduced function
Gross oedema & ascites
CHF

Decks in GI Class (59):