Protein Function Flashcards
A molecule that binds to a protein is called
Ligand
A region in the protein where the ligand binds is called
binding site
Ligands bind to the same noncovalent/ different covalent forces that dictate protein structure?
same noncovalent
characteristics of ligand binding
reversible
specific
transient
What expresses how quickly a reaction takes place or how frequently?
dissociations
What % tells us how good a protewin is bound
50%
since [P] is not always known, what is a convenient way to express theta in terms of
[L}
why is the [P] not always known
biochemist only care about amount of active protein
[L] is a concentration, measured in
M (molar)
Unit of Kd
M
The smaller the Kd, the – affinity
higher the affinity, the tighter the binding
Is binding better always good for the cell
no, sometimes u need weak higher Kd
Oxygen-binding proteins are called
Globins
Because we want to avoid free radicals in solution, what organometallic compounds do we use?
Fe2+ in heme oxidized to Fe3+
The main oxygen storage protein is called
Myoglobin
