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ADT Module 5-8 > PUD > Flashcards

Flashcards in PUD Deck (36)
1

There is a 4x greater incidence of ___ ulcers than ___ ulcers.

duodenal, gastric

2

___ ulcers tend to peak in older pts.

gastric

3

___ ulcers take about 2 wks longer to heal.

gastric

4

Goal w/PUD is to eradicate ___.

H. Pylori

5

___ is the predominant factor for recurrent ulcers, but others include:

H. Pylori, smoking, NSAIDS, hypersecretion, noncompliance

6

Tx for H. Pylori is ___ antibx + a ___ or ___ antagonist.

2, PPI, H2

7

First-line tx for H. Pylori is: ___. Total of ___ pills per day. Take for ___ wks.

Amoxicillin OR Tetracycline + Flagyl + PPI (or H2), 15, 2

8

Examples of H2 antagonists:

ranitidine (zantac), cimetidine (tagamet), nizatadine (Axid), famotidine (pepcid)

9

Ideal duration of tx for duodenal ulcers is ___-___wks, ___-___ wks for gastric, and ___-___ wks for older pt or smoker.

4-6, 8-12, 6-8

10

DOC for H2 antagonists is ___.

famotidine (pepcid)

11

Purpose of H2's is to ___ histamine receptors and block ___.

block, acid

12

Purpose of antacids is not to block acid, but to ___ it. Used for ___ symptom relief.

neutralize, PRN

13

Examples of antacids include:

Calcium carbonate (TUMS), Mylanta, Maalox

14

Limit use of ___ ___ d/t rebound acid effect.

calcium carbonate

15

The medication ___ binds to and protects ulcers from acid and allows for healing of the ulcer.

sucralfate (carafate)

16

DOC for pregnancy is ___ d/t its nonsystemic effects.

sucralfate

17

Cytoprotective agents include:

sucralfate (Carafate), misoprostil (Cytotec), bismuth salts (Pepto-Bismol)

18

___ has antibx effects against H. Pylori and is therefore used in the combination of tx.

bismuth

19

Proton Pump Inhibitors (PPI's) include:

omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), Nexium

20

PPI's have a dramatic ___ in gastric acid by interfering w/the ___/proton pump.

reduction, ATP-ase

21

PPI's should be used for ___-___ wks and heal ulcers ___ than H2's.

4-8, faster

22

Avoid use of ___ while on PPI's d/t drug interaction.

ketoconazole

23

___ are the DOC for tx AND prophylaxis of PUD. They heal ___ than H2's.

PPI's, faster

24

___ are DOC for NSAID-induced ulcers.

PPI's

25

Monitor ___ effects and ___ effects w/H2's.

renal, CNS

26

___ is the only way to conclusively select between GU and DU.

Endoscopy

27

General tx includes: stop ___, minimize ___ use, and avoid ___ foods.

smoking, alcohol, exacerbating

28

Dx H. Pylori w/___.

biopsy

29

H. Pylori needs an ___ environment to live and thrive.

acidic

30

Low pH indicates an ___ environment. High pH indicates an ___ environment.

acidic, alkaline

31

MOC stands for:
MOA stand for:

metronidazole, omeprazole, clarithromycin
metronidazole, omeprazole, amoxicillin

32

It is equipotent whether you give your entire dosing once dly or if you split it up for ___. Whereas, it might be more effective split up for ___.

PUD, GERD

33

Misoprostil (Cytotec) is used for ___-induced gastric ulcers.

NSAID

34

PPI's block ___ acid pathways of acid, gastrin, and pepsin. H2's do not.

ALL

35

___ pump is also known as the proton pump.

ATP-ase

36

Don't combine ___ w/H2's.

PPI's