Quiz 3 - disorders of neuromuscular system Flashcards Preview

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Flashcards in Quiz 3 - disorders of neuromuscular system Deck (68)
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1

myelin in the peripheral nerves comes from.....

Schwann cells

2

myelin quantity and function

heavy - somatic motor, sensory to reflexes
intermediate - touch, proprioception, joint position
light - sharp pain, autonomic motor preganglionic
none - burning, aching, temp, postganglionic autonomic

3

more sensory loss in peripheral or nerve root damage?

peripheral, in nerve root damage there is overlap

4

fasciculations, along with weakness and/or atrophy indicates damage to what?

anterior horn cell or its axons

5

what does weakness with a high firing rate of motor units indicate?

compensation for loss of motor neurons or axons

6

what are the two pediatric inherited anterior horn cell degenerative diseases and who do they affect?

Werdnig-Hoffman - infants
Kugelberg-Welander - children/young adults

7

ALS damage is usually to what?

both upper and lower motor neurons

8

who usually gets ALS

40-60yos

9

weakness in ALS

can be varied between upper and lower motor neurons in single patient

10

CN involvement in ALS

- tonge, face, phalanx, soft palate
- NOT eyes

11

longevity and death in ALS

- 3-5 years
- due to respiratory muscle weakness and superimposed infection

12

ALS involving only upper motor neurons is called

primary lateral sclerosis

13

ALS involving only lower motor neurons is called

progressive muscular atrophy

14

ALS involving only cranial musculature is called

progressive bulbar palsy

15

what drug slows down ALS?

riluzole

16

3 categories of peripheral nerve damage

1) mononeuropathy
2) mononeuropathy multiplex
3) polyneuropathy

17

mononeuropathy is most often due to

trauma
entrapment

18

PE technique for mononeuropathy

Tinel sign, tapping at place of damage for mechanical sensitivity

19

most common mononeuropathy

carpal tunnel syndrome

20

damage to the radial nerve is indicated by

wrist drop

21

nerve damage in thoracic outlet syndrome is in the distribution of the....

ulnar nerve

22

what is radiculopathy?

damage to nerve root

23

causes of radiculopathy in younger and older adults

younger - disc herniation
older - degenerative issues in discs, bones, joints

24

polyneuropathy distribution

- usually symmetrical

25

why are legs affected first in polyneuropathy?

- longer nerves with higher energy demand

26

indication of larger fiber polyneuropathy

- loss of vibration and joint position sense
- can result in poor balance

27

most common symptoms of polyneuropathy

- numbness
- dysesthesias, paresthesias

28

most common causes of polyneuropathy

diabetes mellitus
B12 deficiency
heavy metal exposure
chemo and antivirals

29

diseases that can cause polyneuropathy

Lyme
tertiary syphilis
HIV

30

Guillain-Barre (AIDP) differences from typical polyneuropathy

- rapid course - ether ascending or descending
- severe weakness
- follows diarrheal or viral disease often
- lost reflexes
- high CSF protein levels