Quiz 6 - extrapyramidal Flashcards Preview

SBM neurology > Quiz 6 - extrapyramidal > Flashcards

Flashcards in Quiz 6 - extrapyramidal Deck (17):
1

extrapyramidal

non-cortical regulation and modulation of coordination in anterior horn

2

oxidative stress

inability to detoxify reactive intermediates

3

parkinsonism

tremor
postural instability
rigidity
hypokinesia - decreased bodily movement

4

cogwheeling

sign of hypokinesia

5

chorea

involuntary movement

6

athetosis

involuntary, convoluted, writhing movements of distal extremities

7

hemiballismus

involuntary flailing movements

8

dystonia

sustained muscle contractions cause twisting and abnormal postures

9

the extrapyramidal system is responsible for

- sustained posture
- resting tone
- patterned movements

10

what degenerates in parkinson's?

substantia nigra

11

symptoms of parkinsons

rigidity, bradykinesia, delayed postural reflexes, difficulty initiating movements, resting tremor

12

signs of parkinsons

mask face, stooped posture, increased flexor tone, drooling, shuffling, seborrhea, orthostasis, decreased blinking, soft voice (hypophonia)

13

two mechanisms used in treating parkinsons

agonists of dopamine
antagonists of ACh

14

contrast levodopa and dopamine

levodopa can cross BBB

15

what does carbidopa do?

- blocks dopa decarboxylase
- prevents degeneration of levodopa to dopamine and lessens side affects of levodopa

16

over treatment of parkinsons with dopamine agonists causes

chorea and athetosis

17

surgical procedures for parkinsons

thalamotomy - tremor
palidotomy - rigidity and bradykinesia