Quiz 7 Flashcards Preview

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Flashcards in Quiz 7 Deck (22):
1

pravastatin

Pravachol

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don't take with Alcohol
Lipid levels should be take 4 weeks after initial therapy
stop before major surgery

2

rosuvastatin

Crestor

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
ADR: Arthralgia
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don't take with Alcohol
can be taken with or without meals
report s/s of jaundice or rhabdomyolysis

3

colesevelam

Welchol

hypolipidemic, bile acid sequestrant
Pregnancy category: B
Contraindications: history of bowel obstruction, hyperTG induced pancreatitis,
TG >500
empty powder into glass of water, stir well
take with meal
can be given with HMG-CoaA reductase inhibitor

4

atorvastatin

Lipitor

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
ADR: Arthralgia. Diarrhea, HA
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don't take with Alcohol, or grapefruit juice

5

gemfibrozil

Lopid

Antihyperlipidemic
pregnancy category: C
contraindications: HSR, gall bladder disease, sever renal/ hepatic dysfxn, concurrent repiglinide
ADR: indigestion
report s/s of jaundice or rhabdomyolysis or renal failure

6

fenofibrate

Lofibra

Antihyperlipidemic
pregnancy category: C
contraindications: HSR, gall bladder disease, sever renal/ hepatic dysfxn, nursing mothers
ADR: Hyperhomocysteinemia
take with food depending on dosage form
take 1 hour before or 4-6 hours after bile acid binding resins
don't crush or chew extended release products
products are not interchangeable

7

niacin

Niaspan

Antihyperlipidemic
pregnancy category: C
contraindications: HSR
ADR: Flushing
DI: ezetimibe, cholestyramine, colestipol,HMG-CoaA reductase inhibitor
Start with low dose and titrate up
don't take with alcohol and warm beverages
if d/c may have to start with low dose again
aspirin or NSAIDs may reduce flushing if taken 30 mins before

8

simvastatin

Zocor

HMG-CoaA reductase inhibitor
Pregnancy category X
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes, Azole antifungals, macrolides, HIV protease inhibitors, nefazodone
Don't take with Alcohol, or grapefruit juice
Contact prescriber before starting any new drug therapy

9

omega-3-acid ethyl esters

Lovaza

Antihyperlipidemic
pregnancy category: C
contraindications: HSR
swallow capsule whole- if you can't swallow, puncture hole into capsule and squeeze into glass or porcelain cup
Take with food
seek medical attention if: SOB, rash, chest pain or heart palpitations occur

10

lovastatin

Altoprev

HMG-CoaA reductase inhibitor
Pregnancy category X
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes, HIV protease inhibitors
Don't take with Alcohol, or grapefruit juice
immediate release- take with evening meal
extended release- don't crush or cut
report s/s of jaundice or rhabdomyolysis or renal failure
Contact prescriber before starting any new drug therapy including herbal drugs

11

ezetimibe

Zetia

Antihyperlipidemic, cholesterol absorption inhibitor
Pregnancy category: C
Contraindications: HSR, gall bladder disease, severe renal/hepatic dysfxn, with statins/ pregnancy
take with or without food
can be given with HMG-CoaA reductase inhibitor
take 2 hours before or 4 hours after bile acid sequestrant

12

Pravachol

pravastatin

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don't take with Alcohol
Lipid levels should be take 4 weeks after initial therapy
stop before major surgery

13

Crestor

rosuvastatin

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
ADR: Arthralgia
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don't take with Alcohol
can be taken with or without meals
report s/s of jaundice or rhabdomyolysis

14

Welchol

colesevelam

hypolipidemic, bile acid sequestrant
Pregnancy category: B
Contraindications: history of bowel obstruction, hyperTG induced pancreatitis,
TG >500
empty powder into glass of water, stir well
take with meal
can be given with HMG-CoaA reductase inhibitor

15

Lipitor

atorvastatin

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
ADR: Arthralgia. Diarrhea, HA
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don't take with Alcohol, or grapefruit juice

16

Lopid

gemfibrozil

Antihyperlipidemic
pregnancy category: C
contraindications: HSR, gall bladder disease, sever renal/ hepatic dysfxn, concurrent repiglinide
ADR: indigestion
report s/s of jaundice or rhabdomyolysis or renal failure

17

Lofibra

fenofibrate

Antihyperlipidemic
pregnancy category: C
contraindications: HSR, gall bladder disease, sever renal/ hepatic dysfxn, nursing mothers
ADR: Hyperhomocysteinemia
take with food depending on dosage form
take 1 hour before or 4-6 hours after bile acid binding resins
don't crush or chew extended release products
products are not interchangeable

18

Niaspan

niacin

Antihyperlipidemic
pregnancy category: C
contraindications: HSR
ADR: Flushing
DI: ezetimibe, cholestyramine, colestipol,HMG-CoaA reductase inhibitor
Start with low dose and titrate up
don't take with alcohol and warm beverages
if d/c may have to start with low dose again
aspirin or NSAIDs may reduce flushing if taken 30 mins before

19

Zocor

simvastatin

HMG-CoaA reductase inhibitor
Pregnancy category X
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes, Azole antifungals, macrolides, HIV protease inhibitors, nefazodone
Don't take with Alcohol, or grapefruit juice
Contact prescriber before starting any new drug therapy

20

Lovaza

omega-3-acid ethyl esters

Antihyperlipidemic
pregnancy category: C
contraindications: HSR
swallow capsule whole- if you can't swallow, puncture hole into capsule and squeeze into glass or porcelain cup
Take with food
seek medical attention if: SOB, rash, chest pain or heart palpitations occur

21

Altoprev

lovastatin

HMG-CoaA reductase inhibitor
Pregnancy category X
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes, HIV protease inhibitors
Don't take with Alcohol, or grapefruit juice
immediate release- take with evening meal
extended release- don't crush or cut
report s/s of jaundice or rhabdomyolysis or renal failure
Contact prescriber before starting any new drug therapy including herbal drugs

22

Zetia

ezetimibe

Antihyperlipidemic, cholesterol absorption inhibitor
Pregnancy category: C
Contraindications: HSR, gall bladder disease, severe renal/hepatic dysfxn, with statins/ pregnancy
take with or without food
can be given with HMG-CoaA reductase inhibitor
take 2 hours before or 4 hours after bile acid sequestrant