QUIZ I Intro to Oral Biology Flashcards Preview

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Flashcards in QUIZ I Intro to Oral Biology Deck (27)
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1

what is the craniofacial complex?

head, face, and neck

2

in order to properly diagnose, prognosticate, treat, and evaluate dental diseases and disorders, we must fully understand what?

how normal tissues develop and function

3

what makes up the dentition?

  • teeth
  • enamel
  • dentin
  • cementum
  • bone
  • periodontal ligament

4

describe teeth

  • occupy 20% surface area in the oral cavity
  • masticatory force 500-700 newtons/ 110-160 lbs of force
  • mastication, speech, esthetics, defense, bone health

5

describe enamel

  • 96% mineral
  • non-vital
  • brittle
  • ameloblasts

6

describe dentin

  • ~70% mineral
  • elastic
  • permeable
  • vital
  • odontoblasts

7

describe cementum

  • 50% mineral
  • thin
  • vital
  • attachment site

8

describe bone

  • 50% mineral
  • support
  • remodels continually

9

describe the periodontal ligament

  • hammock
  • fibrous

10

what 3 features form the periodontium?

cementum, bone, and periodontal ligament

11

what is the clinical crown?

the visible portion of the crown that is not covered by gingival tissues

12

what is the anatomic crown?

the entire part of the crown covered in enamel (it is usually larger than the clinical crown in a healthy mouth)

13

describe finding disease genes

nucleus → chromosome → band → gene → mutation

14

describe approaches to identifying disease susceptibility genes

  • linkage analysis
    • studies families with more than one affected individual
  • candidate gene analysis (association study)
    • compares people with the disease to people with the disorder
    • case-control

15

what are 2 forms of genetic variation?

mutation and polymorphism

16

what is a mutation?

  • rare change in the DNA sequence
  • refers to negative effect
  • a form of polymorphism

17

what is a polymorphism?

  • 2 or more alleles in the population
  • may be benign or predispose to disease 
  • present in 1% of the population

18

what are 4 types of mutations?

  • point mutation
  • deletion
  • insertion
  • frame shift

19

what are the 4 main stages in tooth development?

  1. initiation
  2. morphogenesis
  3. dentin and enamel deposition
  4. tooth formation and eruption

dental lamina (mesenchyme and ectoderm) → bud → cap → bell → tooth

20

what is tooth agenesis?

 congenitally missing teeth

21

what is cleidocranial dysplasia?

a condition in which a third layer of teeth is formed

22

what are 4 clinical correlates of enamel?

  • genetic disorders
  • fluorosis
  • febrile/tetracycline use
  • dental caries

23

what are the dentin and pulp cells?

odontoblasts

24

what are 2 clinical correlates of the dentin-pulp complex?

genetic disorders and dental caries

25

what are 5 types of dentin?

  • predentin
  • primary dentin
  • secondary dentin
  • tertiary dentin
  • mantle dentin

26

what are 5 challenges of modulating inflammation?

  • infected pulp tissue
  • inflamed pulp tissue
  • decay
  • abscess
  • inflamed ligament

27

name the 6 principal fiber groups within the periodontium

  • transseptal ligament
  • alveolar crest group
  • horizontal group
  • oblique group
  • apical group
  • interradicular group