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Flashcards in Remember! Deck (20)
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0

Expected increase in Hg and Hct for every unit of packed RBC

For every unit of PRBC
- 10 points Hg
- 3 points Hct

1

Disease with problem in mismatch repair

Lynch syndrome
- HNPCC
- hallmark: microsatellite instability

2

Enzyme inhibited by 5-FU

Thymidylate synthase

3

Disease that has a problem with thymine dimers

Xeroderma pigmentosum - precursor to all skin CAs

4

Dacrocytes

Aka tear drop cells seen in Primary Myelofibrosis

5

Codocytes

Aka target cells

6

Echinocytes

Aka burr cells - RBCs with spikes

7

Protein absent in smooth muscle

Troponin

8

Functions as troponin c in smooth muscle

Calmodulin

9

Functions as troponin I in smooth muscle

Caldesmon
Calponin

10

Cyclooxygenase product that inhibits platelet aggregation and causes vasodilation

PGI2
Prostacyclin

11

Fabry's disease - inheritance? Deficiency? What accumulates?

X-linked
Alpha- galactosidase
Globoside

12

Gaucher disease - inheritance? Deficiency? What accumulates?

AR
B-glucosidase
Glucocerebroside

13

Krabbe disease - inheritance? Deficiency? What accumulates?

AR
B-galactosidase
Galactocerebroside

14

Nieman Pick disease - inheritance? Deficiency? What accumulates?

AR
Sphingomyelinase
Sphingomyeline

15

What part of the antibody attaches to the antigen?

Variant portions of both light and heavy chains at the amino terminal end
(Fab region)

16

Granular casts

ATN

17

Fatty cast

Nephrotic syndrome

18

Waxy cast

Chronic renal failure

19

Acid- base problem with loop and thiazide diuretics

Metab alkalosis