renal-1 into Flashcards

(56 cards)

1
Q

what does renal mean

A

anything to do with the kidneys

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2
Q

what is the most obvious function of the kidneys

A

to filter on the blood, plasma regulation

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3
Q

what do kidneys regulate (2 things)

A

blood volume and pressure

acid base balance

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4
Q

what is entailed in blood volume and pressure in kidney regulation

A

water concentration, fluid volume, inorganic ion composition

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5
Q

what do kidneys excrete

A

urea, uric acid, creatinine, bilirubin, foreign chemicals

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6
Q

what is urea

A

protein breakdown

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7
Q

what is uric acid

A

nucleotide breakdown

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8
Q

what is creatinine

A

MUSCLE BREAKDOWN WAHHHH

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9
Q

what is bilirubin

A

RBC breakdown

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10
Q

Who does glucogenogenesis

A

Kidneys

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11
Q

when does gluconeogenesis occur

A

during starvation

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12
Q

what do kidneys secrete

3 examples

A

hormones and enzymes
erythropoietin
1,25-dihydroxy Vitamine D
Renin

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13
Q

what is erythropoietin

A

helps synthesize RBC, secreted by kidney cells

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14
Q

what is 1,25-dihydroxy vitamin D

A

linked close to phosphate regulation

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15
Q

what is renin

A

enzyme that helps balance sodium and ion composition

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16
Q

what is intracellular fluid

A

fluid inside the cell

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17
Q

what is extracellular fluid

A

fluid ourside of the cell (plasma+interstitial fluid + cerebrospinal fluid)

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18
Q

what is plasma

A

non-cellular part of blood, fluid inside blood vessels

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19
Q

what is interstitial fluid

A

fluid outside the cell but not in circulatory system (not plasma)

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20
Q

what percent of total body weight is water

A

60%

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21
Q

what percent of total body weight is intracellular fluid

A

40%

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22
Q

what percent of total body weight is extracellular fluid

A

20%

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23
Q

what is the relative intra and extracellular amounts of Na

A

more Na out than in

24
Q

what is the relative intra and extracellular amounts of K

A

more K in than out

25
what is the relative intra and extracellular amounts of Ca
more Ca out than in
26
what is the relative intra and extracellular amounts of Cl
more Cl out than in
27
what is osmolarity
the number of solutes per unit volume of solution (mol/L)
28
what is 1 osmol mean (equal to)
1 mole of solute particles
29
what does low osmolarity mean
high water concentration | low solute
30
what does high osmolarity mean
low water concentration | high solute
31
what is diffusion
process of movement of molecules from one location to another as a result of random thermal motion
32
what is osmosis
net diffusion of WATER across SELECTIVELY PERMEABLE MEMBRANe (high to low water conc)
33
what is osmotic pressure
the pressure necessary to prevent solvent movement (osmosis)
34
what is the point of osmotic pressure
to make sure it doesn't expand too much
35
what is the opposing pressure required to stop osmosis completely
osmotic pressure
36
what is tonicity determined by
the concentration of non penetrating solutes of an extracellular solution relative to the intracellular environment of a cell
37
what is non penetrating solute | examples
they need channels to pass through the membrane | Na+ K+ Cl-
38
what is isotonic
same osmolarity inside and outside of cell
39
what is hypertonic
higher osmolarity outside than inside the cell | they shrink
40
what is hypotonic
lower osmolarity outside than inside the cell | they grow
41
which direction does water flow (osmolarity)
water flows from low osmolarity to high osmolarity
42
what is normal osmolarity in a cell
300mOsm/L
43
what differentiates tonic and osmotic (isotonic vs/ isoosmotic, etc)
saying -osmotic instead of -tonic (iso, hypo, hyper) does not mention whether or not it is a penetrating solute (tonic non penetrating)
44
what is filtration
movement of solute/water out of the plasma
45
what is absorption
movement of solute/water into the blood
46
what is movement of solute/water into the blood
absorption
47
what is movement of solute/water out of the plasma
filtration
48
what is net filtration pressure
Pc + πIF – PIF -πc
49
where is capillary hydrostatic pressure (Pc) highest and what does this cause
more at the arterial end, so more filtration then
50
what is interstitial fluid hydrostatic fluid
pressure that comes from the interstitial fluid
51
what is πc
osmotic force due to plasma protein concentration
52
what direction is πc
inwards towards capillaries
53
what direction is πIF
outwards from capillaries
54
what direction is PIF
inwards towards capillaries
55
what direction is Pc
outwards from capillaries
56
what is πIF
osmotic force due to interstitual fluid protein concentration