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Flashcards in Renal Deck (72):
1

spikes in GBM

membranous glomerulonepropathy

2

JG cells

smooth muscle cells with renin granules

3

renal hypoperfusion

increase renin secretion by JG cells

4

low C3

PSGN

5

eosinophilic casts

Bence Jones + Tam Horsfall protein (multiple myeolma)

6

finasteride

5 alpha reductase inhibitor
decrease prostate volume

7

alpha3 chain of type IV collagen

good pastures

8

lumpy bumpy apperance

PSGN

9

salicylate toxicity

resp alkalosis followed by metabolic acidosis

10

rubber manufacturing

transitional cell bladder cancer

11

polycystic renal disease

decrease vit D

12

Inulin

freely filtered
not reabsorbed or secreted

13

FF =

GFR/RPF or
GFR / (1 - hct) x RBF

14

PAH

excreted amount >> filtered
net secretion

15

PAH lowest concentration

bowman's capsule

16

loss of antithrombin III

thromboembolic events
flank pain, gross heamturia

17

filtration rate =

inulin clearance x plasma concentration

18

excretion rate =

inulin clearance x plasma concentration - tubular reabsorption

19

RPGN cells

monocytes, macrophages, FIBRIN

20

interstitial nephritis

penicillins, NSAIDs

21

RCC paraneoplastic syndromes

EPO
ACTH
PTH

22

transitional cell carcinoma associatins

phenacetin
smoking
aniline dyes
cyclophophamide

23

RPGN

1 - GP
2 - immune complex
3 - wegners

24

IgA deposits

Berger's dz

25

DPGN

SLE

26

MPGN

HBV, HCV

27

FSGS

HIV

28

membranous nepropathy

SLE
infections
solid tuors

29

RBC casts

glomerulonephritis

30

WBC casts

trnasplant rejection
pyelonephritis

31

fatty casts

nephrotic syndrome

32

granular casts/muddy brown casts

ATN

33

afferent arteriole constriction

decrease RPF, GFR

34

efferent arteriole constriction

decrease RPF
increase GFR

35

horseshoe kidney

turner's association

36

potter's syndrome association

posterior urethral valves
ARPKD

37

Clearance < GFR

reabsorption

38

Clearance > GFR

secretion

39

Renal Plasma Flow Calculation

RPF = urine PAH x urine flow rate / plasma PAH

40

Renal Blood Flow Calculation

Renal Plasma Flow / 1 - HCT

41

increase plasma protein concentration

decrease GFR

42

decrease plasma protein concentration

increase GFR

43

Aldosterone

reabsorps Na
secrete K and H

44

Foscarnet

CMV retinitis treatment
causes hypocalemia and hypomagnesium

45

PLA2R Antibodies

gluomerulonephritis = membranous nephropathy

46

RCC originates from

proximal renal tubules

47

early detection of diabetic neuropathy

microalbuminemia

48

mannitol

used for cerebral edema
side effect - pulmonary edema

49

vasopression/ADH acts on

medullary segment of collecting ducts

50

CKD manifestations

low calcium --> osteodystrophy

51

Amph B side effects

hypokalemia and hypomagnesium

52

ATN initiation

ischemic injury

53

ATN maintenance

decreased urine
increase CR/BUN
hyperkalemic

54

ATN recovery

low K, Mg, Po4, Ca

55

MCD - type of proteinuria

selective
albumin loss >>> bulky proteins

56

tubular re-epithelization is outcome of

ATN

57

impermeable to H20

ascending limb

58

PSGN prognosis

better with younger age

59

Neprhotic Syndrome

- proteinuria
- hypoalbuminemia
- hyperlipidemia

60

Nephrotic Syndrome caused by

decreased oncotic pressure

61

clear cell has

high lipid/glycogen content

62

substances that are neither secreted or reabsorbed

mannitol
inulin

63

substances that are reabsorbed

glucose
urea
sodium

64

substances that are secreted

PAH
creatinine

65

ceramid trihexoside accumulation

Fabry Disease

66

Fabry disease

angiokeratomas
renal failure

67

primase

RNA polymerase

68

lactic acidosis decreases what enzyme

pyruvate DH

69

aceI cause

constriction of efferent arteriole
vasoconstriction
aldosterone

70

uric acid precipitation

due to low urine PH
DCT, CD

71

metameniphic mesoderm becomes

glomeruli
bowman's capsule
PCT, loop of henle, DCT

72

ureteric bud becomes

CTubules, CDuct
calyces, renal pelvis, ureters