Respiratory Embryology Flashcards Preview

Year 1: Respiratory > Respiratory Embryology > Flashcards

Flashcards in Respiratory Embryology Deck (12):
1

why germ layer forms the respiratory system?

endoderm forms the lining of the trachea and bronchial tree
all other lung tissue (smooth muscle, cartilage...) is formed by the by visceral mesoderm

2

tracheoesophageal fistula

an abnormal connection between the oesophagus and the trachea. It's a common birth defect

3

stages of lung maturation

embryonic (26 days- 6 weeks)
pseudoglandular (6-16 weeks)
canalicular (16-28 weeks)
saccular (28-36 weeks)
alveolar (36 weeks- early childhood)

4

function of type I pneumocytes

they are flattened, thin, squamous: this gives them a thin distance for gaseous exchange

5

function of type II pneumocytes

these retain their cuboidal shape and produce surfactant, which prevents the lungs from collapsing

6

respiratory distress syndrome

causes about 20% of the deaths of all newborns. Occurs due to lungs collapsing due to premature babies not having enough surfactant

7

oesophageal atresia

birth defect which causes the oesophagus to end in a blind-ended pouch rather than connecting normally to the stomach

8

embryonic stage events?

respiratory diverticulum forms. Initial branching gives lungs, lobes and segments

9

pseudoglandular stage event?

14 more generations of branching. Terminal bronchioles

10

canalicular events?

terminal bronchioles--> respiratory bronchioles--> alveolar ducts

11

saccular events?

terminal sacs form, capillaries establish close contact

12

alveolar events?

alveoli mature