respiratory pathology Flashcards

(31 cards)

1
Q

what is a spirogram

A

A tracing of the relationship between maximal expiratory airflow and time

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2
Q

what are the 5 components of a spirogram

A
  • forced vital capacity
  • residual volume
  • total lung capacity
  • inspiratory capacity
  • functional residual capacity
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3
Q

what are 2 ways to test for lung volume

A

helium dilution (difference in helium conc during inhale and exhale)
body plethysmography (measures pressure change in sealed booth)

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4
Q

whats the difference between obstructive and restrictive disorders

A

obstructive = airway obstruction
restriction = functional reduction in lung volume

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5
Q

how can u identify obstructive or restrictive disorders

A

through spirometry and peak flow

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6
Q

what is FEV1

A

forced expiratory volume in 1 second
(total volume of gas exhaled int he first second of a maximally forced exhalation after maximal inhalation)

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7
Q

what can a spirometer measure

A

FEV1 and FVC (forced vital capacity)

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8
Q

how can you measure both FEV1 and FVC

A

using vane anaemometer

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9
Q

what does a vitalograph show

A

plots volume expired against time (shows plateau)

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10
Q

what does a flow-volume curve show

A

plot volume expired against flow (derived from vitalograph)

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11
Q

check iPad notes for graph images

A
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12
Q

what does PEFR stand for and what does it mean

A

peak expiratory flow rate
- the maximal expiratory flow rate

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13
Q

what would show on graph due to obstructive spirometry

A

FEV1 is lower (flatter gradient)
- but same FVC reached as lung volume is unchanged
- FEV1:FVC ration is lower

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14
Q

what is radial traction

A

the elastic fibres of the surrounding alveoli pull on the walls of small airways and hold them open

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15
Q

what can show on graph due to restrictive spirometry

A

FEV1 middle reduced
- FVC is reduced to
- because both are lowered, FEV1:FVC ration stays similar

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16
Q

is pulmonary fibrosis obstructive or restrictive

17
Q

is COPD obstructive or restirictive

A

obstructive (airways collapse and get blocked by mucous walls)

18
Q

what 2 components are part of the work of breathing and what are they

A
  • compliance (expandability of lungs and chest wall)
  • resistance (ease which gas flows through conducting airways)
19
Q

decreasing compliance or increasing resistance leads to what?

A

decrease compliance = restrictive
increasing resistance = obstructive

20
Q

define complience / equation

A

change in unit volume per unit pressure
compliance = volume/pressure

21
Q

what feature of lungs help passive exhalation

A

elastic recoil of lungs which is one of the forces that help us passively exhale

22
Q

what are 2 main properties of lung that affect its compliance

A
  1. elastic fibres in lung parenchyma (tissue)
  2. water tension in alveoli
23
Q

explain how the water molecules inside alveoli can cause collapsing

A
  • h20 molecules in alveolus have cohesive force
  • the leads to inward pressure
  • if left unchecked can lead to the collapse of the alveoli, decreased compliance and etc
24
Q

how is prevention of alveoli collapse due to water cohesion taken care of

A

type 2 pneumocystis in alveoli release surfactants reducing this force

25
the lung has elastic recoil pulling inwards and chest wall has natural pull outwards
26
what is normal intrapleural pressure
negative throughout normal respiratory cycle (755mmHg) inside = 760mmHg outside = 760mmHg
27
what happens if theres hole in pleural
pressure equalises and lung collapses (pneumothorax)
28
what is poiseuilles law
flow is proportional to radius^4
29
what causes breath sounds
turbulent airflow going through airway
30
give some examples of meds used to open airway
beta 2 agonist (blue inhaler) corticosteroids (brown inhaler) leukotriene receptor antagonist etc
31
what does IRV/ERV stand for
inspiratory/expiratory reserve volume