RESPIRATORY SYSTEM Flashcards
(220 cards)
what is the prevalence of acute asthma in children and young adults?
a) 5%
b) 15%
c) 25%
d) 35%
b) 15%
is acute asthma more common in developed or developing countries?
developed
what is the name for chronic inflammation of the large airways?
bronchospasm
name one hypothesis for the development of asthma
hygeine
what antibody mediates an asthma allergic reaction?
IgE
name 5 cells which are recruited during an asthma attack
mast cells dendritic cells eosinophils lymphocytes T helpers
what epithelial and basement re-modelling occurs in asthma?
loss of cilia
increase of mucus cells
thickened basement membrane
what happens to smooth muscle in the airways in chronic asthma?
hyperplasia from chronic infection
What are the four main symptoms of worsening asthma?
SOB at night
Wheeze at night
Cough
Chest tightness
what would occur upon percussion of a patient with asthma?
hyper resonance
is the airway obstruction of asthma reversible or irreversible?
reversible
what 4 things cause bronchial inflammation in asthma?
infiltration of immune cells
muscle hypertrophy
mucus plugging
epithelial damage
What are the signs of acute asthma attack?
PEFR <35%-50% RR= >25 HR=> 110pbm Can't speak full sentance Cyanotic
What is the signs for fatal asthma attack?
PEFR <35%
Poor respiratory effort and silent chest sound
Pa02= <8
O2 sats= 92% on air
Unconsciousness and arrhythmia may be present
What is the atopic triad commonly seen in medical/family history of a patient with asthma?
The patient or within the family they are suffering from
Eczema
Asthma
Hay fever
give 4 examples of exacerbating factors for asthma
cold air exercise allergens pets existing atrophy acid reflux
what is the difference between intrinsic and extrinsic asthma?
intrinsic = no known cause (chemical/exercise induced) extrinsic = allergen
what two measurement test might you recommend for a patient with suspected asthma?
peak expiratory flow
spirometry
what type of drug is salbutamol and terbutaline and how are they administered and how often?
beta agonist
inhaled
short acting up to 4x daily
Give an example of an inhaled steroid for asthma or COPD
Corticosteriods such as beclometasone, fluticasone and budesonide
why are inhaled steroids given for asthma and how often are they administered?
prevention
two times daily
give 3 side effects of inhaled steroids
reduced bone mineral density
growth failure
adrenal suppression
oral candida
What is the treatment for acute asthma attack?
O SHIT ME
Oxygen 15L non rebreathable mask
Salbutamol 5mg Nebulizer ( change oxygen to 6L/8L) = every 15-20 minutes
Hydrocortisone 200mg Iv or prednisolone 40mg oral
Ipratropium bromide Iv 0.5mg 4-6 hours
Theophylline
Magnesium Sulphate 2g Iv
Extra help
how many people are affected by COPD in the UK?
a) 50
b) 50,000
c) 500,000
d) 1.5 million
d) 1.5 million