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Flashcards in Restrictive Lung Diseases Deck (22)
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1

Which structure(s) are mainly damaged in interstitial lung disease?

Alveolar walls and lumen
Causes impaired gas exchange

2

CO2 and O2 exchange is impaired. True/False?

False
CO2 exchange is unimpaired as it is very soluble

3

How can consolidation of alveolar spaces arise?

Infection (pneumonia)
Infarction (PE)
BOOP (none of above)

4

What is sarcoidosis?

Non-caseating granulomatous disease (Type IV hypersensitivity) of unknown aetiology

5

Sarcoidosis is less common in smokers. True/False?

True!

6

List some clinical signs of sarcoidosis

Erythema nodosum
Bilateral hilar lymphadenopathy
Arthritis
Fever
Lung infiltrates
Multi-system damage

7

Is treatment given for sarcoidosis?

Oral steroids and immunosuppressives ONLY IF vital organs are being affected/chronic

8

Symptoms of EAA occur rapidly. True/False?

False
Typically several hours after exposure

9

How is EAA treated?

Antigen avoidance
Oral steroids if very breathless

10

What is the most common ILD?

Idiopathic pulmonary fibrosis

11

What is the proposed aetiology of idiopathic PF?

Imbalance in fibrotic repair, resulting in scarring of the lung

12

Name some drugs which can cause IPF

Amiodarone, bleomycin, methotrexate

13

List some clinical signs of IPF

Progressive breathlessness
Clubbing
Bilateral fine inspiratory crackles

14

What is pneumoconiosis?

ILD caused by inhalation of occupational dusts

15

Describe the early and late stages of ILD

Early: alveolitis (inflammatory infiltrates)
Late: scarring

16

Lung tissue becomes fibrous in IPF. What is the physiological consequence of this?

Reduced compliance (not as elastic)

17

Define asbestosis

Fibrosis due to asbestos exposure

18

IPF is commoner in females. True/False?

False
Commoner in males

19

What is heard on auscultation in IPF?

Fine bilateral end-inspiratory crackles

20

What is extrinsic allergic alveolitis?

Inflammation in airways due inhalation of foreign antigens, usually from animals

21

Smokers have increased risk of EAA. True/False?

False
Decreased risk!

22

What is heard on auscultation in EAA?

Coarse end-inspiratory crackles