Tuberculosis Flashcards Preview

1MB Respiratory > Tuberculosis > Flashcards

Flashcards in Tuberculosis Deck (14)
Loading flashcards...
1

Which bacteria is the commonest cause of TB?

Mycobacterium tuberculosis

2

What is the primary test for TB?

PCR

3

TB involves non-caseating necrosis. True/False?

False
It is caseating

4

What is interferon gamma testing re TB?

Measures how much IFG is released from T cells in response to stimuli (MTB)

5

Which 4 drugs are used for TB?

Rifampicin
Isoniazide
Pyrazinamide
Ethambutol

6

Start of with 4 months on RI, then 2 months on PE. True/False?

False
2 months on RIPE, then 4 months on RI

7

If patient has TB affecting CNS, what is the treatment course?

2 months on RIPE, then 10 months on RI

8

List some adverse reactions of Rifampicin

Hepatitis
Orange-red urine
Flu syndrome

9

List some adverse reactions of Isoniazide

Hepatitis
Peripheral neuropathy

10

List some adverse reactions of Pyrazinamide

Hepatitis
Anorexia, vomiting
Hyperuricaemia

11

List some adverse reactions of Ethambutol

Colour blindness, developing into blindness
Arthralgia

12

What proportion of the world population is affected by TB?

1/3

13

Which components make up the necrosis in TB?

Epitheloid cells and Langhan’s giant cells, causing formation of Ghon focus

14

When might the Mantoux/tuberculin skin test for TB be false negative?

If patient has had a BCG vaccination