Rhinitis and Rhinorrhoea Flashcards Preview

Respiratory > Rhinitis and Rhinorrhoea > Flashcards

Flashcards in Rhinitis and Rhinorrhoea Deck (12):
1

What does rhinitis cause?

Acute or chronic inflammation of the nasal mucosa

2

In allergic rhinitis, inhalation of the allergen increases what?

Specific IgE levels

3

What does IgE bind to?

Receptors on mast cells and basophils

4

What does re-exposure to the antigen cause?

Mast cell and basophil degranulation

5

What does degranulation of mast cells and basophils cause release of?

Histamine, CysLT, tryptase, prostaglandins

6

What is involved in the delayed response which causes congestion and obstruction?

Lymphocytes and eosinophils

7

What is non-allergic rhinitis?

Rhinitis not involving IgE

8

What do rhinitis and rhinorrhoea cause in increase of?

Mucosal blood flow, blood vessel permeability or both

9

How do you treat the anti-inflammatory aspect?

Glucocorticoids

10

How do you block the mediators?

Histamine, CysLT1 receptor antagonists

11

How do you target nasal blood flow?

Vasoconstrictors

12

How do you target the antiallergic side?

Sodium cromoglicate