RNA Viruses Flashcards

(74 cards)

1
Q

all RNA virus are __ stranded except __

A

single stranded

except Reo/rota group which is double stranded

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2
Q

all negative single stranded RNA viruses are ___ and ___

A

helical and enveloped

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3
Q

what are the 3 naked RNA viruses

A

Calici, Pico, and Reo RNA viruses

CPR

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4
Q

all hepatitis viruses are __ except which?

A

RNA

except hepatitis B - which is DNA

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5
Q

all hepatitis viruses are spread by ___ except which?

and how are they spread?

A

oral fecal route

except B and C - spread by sex, blood transfusions, or IV drugs

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6
Q

what do hepatitis viruses cause

A
jaundice 
fever 
anorexia 
vomiting 
tender hepatomegaly
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7
Q

what virus causes hepatitis C

A

Flavivirus

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8
Q

what is the most common transmission of hepatitis C

A

IV drug use and tattoos - 40%

sex and blood transfusion - 20% f

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9
Q

what is hepatitis C characterized by

A

carrier state
cirrhosis
primary hepatocellular carcinoma**

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10
Q

what virus causes hepatitis A

A

Picornavirus

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11
Q

how is hepatitis A transmitted

A

oral-anal route

oral-fecal route

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12
Q

what causes hepatitis D

A

hepatitis B infection

hepatitis D is defective unless accompanied with hepatitis B infection

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13
Q

what virus causes hepatitis E

A

calicivirus

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14
Q

how is hepatitis E transmitted

A

oral-anal route
oral-fecal route
(traveling)

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15
Q

human immunodeficiency virus is caused by what

A

retrovirus - lentivirus subfamily

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16
Q

how is HIV transmitted

A

sex and blood transfusion

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17
Q

how does HIV lead to AIDS

A

the retrovirus destroys the CD4 T helper cells

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18
Q

what are the four stages of HIV/AIDS

A

flu like illness - acute

feeling fine - latent

falling CD4 T cell count causes recurrent oppurtunistic infections (such as cryptococcus meningitis, cytomegalovirus retinitis, candidiasis, cryptosporidium diarrhea)

pneumocysitis jiroveci pneumonia - final crisis

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19
Q

what are other names from measles

A

rubeola or 1st disease

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20
Q

what virus causes measles

A

paramyxovirus

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21
Q

how is measles spread

A

aerosol droplets

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22
Q

what does measles cause

A

koplik spots - white lesion surrounded by red ring around buccal mucousa

coryza - inflammation of mucous membrane in nose

conjunctivitis

maculopapular erythematous rash

syncytia - giant multinucleated cells

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23
Q

what virus causes mumps

A

paramyxovirus

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24
Q

how is mumps transmitted

A

direct contact and aerosol droplets

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25
what does mumps cause
parotitis - parotid gland enlargement* pancreatitis orchitis (inflammation of testicle)
26
what are other terms for Rubella
german measles or 3rd disease
27
what virus causes rubella
togavirus - rubivirus specifically
28
how is rubella transmitted
aerosol droplets
29
what does rubella cause
sore throat cervical lymphadenopathy maculopapular erythematous rash congenital infection in kids in first 10 weeks
30
what virus causes influenza
orthomyxovirus
31
what does influenza cause
fever sorethroat severe myalgia
32
what virus causes the common cold in adults and gastroenteritis in infants
coronavirus
33
how is common cold transmitted
aerosol droplets
34
what does the common cold cause
fever sorethroat runny eyes runny nose
35
what virus causes a upper respiratory tract infection
rhinovirus of picornavirus family
36
what does URTI cause
runny eyes nose sorethroat fever
37
what virus causes the infant disease known as croup
parainfluenza virus - paramyxovirus
38
what does croup cause
braking cough stridor - whistling on breathing hoarseness
39
what virus causes childhood dysentery (bloody diarrhea)
coxsackie virus of the picoRNA family
40
what virus causes rabies
rhabdovirus
41
what is present in brain tissue in a rabies patient
negri bodies
42
what shape is the rhabdo virus that causes rabies
bullet shaped
43
how is rabies transmitted
raccoons, bats, and skunk bites are more common in US than dog bites
44
what does rabies cause
``` hydrophobia dysphagia agitation paralysis coma ```
45
what virus causes poliomyelitis
picornavirus
46
what does poliomyelitis cause
flaccid muscle paralysis (LMN sign) due to destruction of ventral or anterior horn cell damage
47
what does "ARBO" mean in the term ARBO viruses
arthropod borne
48
what are ARBO viruses caused by? arthropods obviously, but what virus specifically? exceptions?
flavivirus (w and ve encephalitis toga ??) except california encephalitis which is bunya virus
49
what are 4 ARBO viruses
``` DEWY dengue fever encephalitis west nile fever yellow fever ```
50
how is encephalitis causing viruses spread? what vector?
mosquitos
51
what are the 3 different kinds of encephalitis? | what are the viruses that cause them?
western encephalitis - flavivirus /togavirus ?? venezuelan equine encephalitis - flavivirus /toga ?? california encephalitis - bunya virus
52
what virus causes yellow fever? | and what is its vector
flavivirus aedes aegypti mosquito (note: same vector and virus as dengue fever but different symptoms - no jaundice)
53
what are the symptoms of yellow fever
fever and juandice
54
what virus causes west nile fever? | and what is its vector?
flavivirus cullex pipiens mosquito
55
what virus causes dengue fever? | and what is its vector?
flavivirus aedes aegypti mosquito (note: same vector and virus as yellow fever but different symptoms - jaundice)
56
what are the 4 categories of RNA viruses
positive sense negative sense ambisense double stranded
57
which RNA virus is acid labile
rhinovirus
58
what virus is the leading cause of the common cold
rhinovirus | coronavirus
59
SARS stands for what associated with what virus
severe acute respiratory syndrome coronavirus
60
norwalk virus is what kind of virus
calicivirus
61
how does someone get infected by norwalk virus
contaminated food | fecal oral route
62
what does norwalk virus cause
gastroenteritis
63
what is another term for breakbone fever
dengue fever
64
which virus has club shaped surface projections that give its appearance
coronavirus
65
how is yellow and dengue fever transmitted to humans
monkeys to mosquitos to humans
66
what fever/virus causes eosinophilic hyaline masses called councilman bodies in the infected liver cells
yellow fever - ARBOvirus
67
what is the leading cause of arboviral encephalitis in the US
west nile virus
68
echoviruses are what type of viruses
picornavirus
69
echoviruses cause what
meningitis, skin rash, heart disease
70
what viruses contain hemagglutinin neuraminidase
paramyxoviruses
71
what type of virus is ebola virus
filovirus
72
what does ebola cause
african hemorrhagic fever then death
73
what is caused by a negative reaction to aspirin when taken for a viral infection such as influenza
reyes syndrome causes fatty liver and encephalopathy
74
influenza contains what specifically that makes it necessary to vaccine yearly
antigenic shift or drift drift - small mutation shift - big mutation causes flu so thats why we take vaccine yearly