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Flashcards in SA Ascarids Deck (19):
1

Name the three main ascarids of SA and their primary hosts.

Which are considered zoonotic?

Toxocara canis, cati, Toxascaris leonia

Canis and cati are zoonotic

2

Describe the morphology of Toxocara spp.

  • Large, white, up to 10cm adults
  • Inflated cuticle forms allae - more pronounced in cati
  • Toxocara (xx toxascaris) have a cuticular protrusion

3

Describe the morphological features of Toxocara eggs.

  • Large, thick pitted shell
  • Spherical
  • Filled with dark brown undifferentiated morular

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4

Describe the morphological features of Toxascaris eggs.

  • Oval
  • Inside morular doesn't fully fill the egg
  • Difficult to differentiate in a mixed population

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5

What clinical signs are associated with Toxocara/ Toxascaris related disease?

  • Asymptomatic in adults
  • With heavy puppy burdens 
    • Pot bellied
    • Poor wt gain
    • Intestinal/ bilary obstruction
    • No diarrhoea
  • May show worm hypersensitivity - coughing 

6

How can Toxocara/ Toxascaris be diagnosed/ controlled in dogs?

  1. Diagnosis - Clinical signs, signalment, salt flotation, adult worms passed in vom/faeces
  2. Control - 
    1. Intestinal stages - BZ/ML
    2. TPT - FBZ from 42 days gestation
    3. Regular worming 
      1. 2,4,6, weeks of age
      2. 3,6 months
      3. Then every 3-6 months

7

Outline the lifecycle and modes of transmission of Toxocara canis.

Describe the migratory pattern of Toxocara canis.

Transmission

  • Ingestion of infective eggs containing L2 by dog
  • TPT - Transplacental transmission - L2 cross placenta at d40 of gestation after being arrested in muscle
  • TMT - Transmammary transmission - L2 enter puppies through L2 in milk

Hepatotracheal migration - L2 migrates from SI to liver to lungs. --> coughed up and swallowed - reproduce and eggs are shed in faeces

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8

What is the PP for toxocara in adult dogs?

How does this differ in puppies and why?

Adults: 4-6 weeks 

Puppies: 3 weeks - L2 infect puppies (not eggs as in adults)

9

Which stage of the Toxocara canis are infective?

Larvated egg stage 

10

Which human group is most at risk of Toxocara canis infection?

Children - kids similarly curious as dogs!

11

How do the infection and incidence rates of Toxocariasis compare?

What clinical signs are associated with the disease

Infection rate is high but incidence rates of disease are low.

Aberant migration of larva to the eye (often retina), this may be misdiagnosed as a tumour. Hypersensitivity causes blindness

12

How can occular toxocariasis disease be controlled/ prevented?

  1. Prevent environmental contamination with eggs (very resistent once present)
    1. Educate pet owners - regular worming
    2. Hygiene - wash hands!

13

Which anthelmintics are used in the control of Toxocara in dogs and cats?

  1. ML - Selamectin, milbemycin, moxidectin
  2. FBZ, PYR
  3. Emodepside

14

How does the lifecycle of Toxocara cati differ to Toxocara canis?

  1. Ingestion of L2 eggs - migration
  2. Ingestion of paratenic host - no migration 
  3. TMT - no migration
  4. No TPT

15

How does the Toxascaris leonina life cycle differ to Toxocara?

  1. Infection occurs only by ingestion of L2 eggs and paratenic hosts
  2. No TMT or TPT

16

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Alae folds of Toxocara canis - restricted on one side

17

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Alae of Toxocara cati - more pronounced than in canis

18

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Egg of Toxascaris leonina - egg is oval with the inside morula not completely filling the egg

19

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Toxocara egg - round, brown with thick pitted shell