SECRETS GI - IBD Flashcards

1
Q

IBD

A

Crohn’s

Ulcerative colitis

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2
Q

Crohn’s assoc

A

Ashkenazi Jews

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3
Q

UC assoc

A

ppl who just QUIT smoking

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4
Q

Crohn’s location

A

anywhere
mostly terminal ileum

skip lesions
spares rectum

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5
Q

UC location

A

limited to colon

continuous from rectum

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6
Q

Crohn’s wall thickness

A

transmural

‘cobblestone’ appearance of mucosa

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7
Q

UC wall thickness

A

mucosal only

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8
Q

Crohn’s complications

A

strictures, fistulas, abscess, malabsorption, colon cancer

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9
Q

UC complications

A

toxic megacolon, hemorrhage, primary sclerosing cholangitis, ++ colon cancer

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10
Q

Crohn’s derm assoc

A

erythema nodosum

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11
Q

UC derm assoc

A

pyoderma gangrenosum

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12
Q

Crohn’s other assoc

A

arthritis, aphthous ulcers, uveitis, perianal fistulas, cholelithiasis

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13
Q

UC other assoc

A

uveitis

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14
Q

Hirschsprung’s disease

A

neural crest cells that form myenteric plexus fail to migrate to colon

rectum is always involved

assoc with down syndrome

tx surgical resection

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15
Q

fat-sol vitamins IBD assoc

A

Crohn’s

terminal ileum - where B12 is absorbed & bile salts reasorbed (diarrhea)

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16
Q

Crohn’s sx tx

A

cholestyramine

17
Q

IBD tx

A

sulfasalazine

precursor to 5-aminosalicylic acid (anti-inflam)
converted in distal ileum, colon

18
Q

UC + obstructive jaundice

A

primary sclerosing cholangitis

fibrosis of large bile ducts

19
Q

Anklyosing spondylitis

A

bamboo spine
bilateral sacroilitis

Crohn’s