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Nutrition 1 Part 2 > Selenium > Flashcards

Flashcards in Selenium Deck (27):
1

richest source of Se is

meat

2

why does fish have low bioavailability of Se

mercury content

3

selenium is absorbed in the

SI

4

what vitamins enhance the absorption of Se

Vitamin A , C , E

5

what inhibits the absorption of Se

phytate, heavy metals (mercury)

6

selenium is bound to various proteins in order to travel through the blood such as ___ , __ and ____

VLDL
LDL
selenoprotein P

7

selenium concentrates in the

thyroid gland
kidney
liver
heart
pancreas
muscle

8

functions of selenium

cofactor in selenium dependent enzymes
immune function

9

what are the selenium dependent enzyemes

iodothyronine deiodinases (IDI)
glutathione peroxidases (GPX)
selenoprotein P (SEL P)

10

most of the biologically active T3 in teh circulation and inside cells is created by the removal of one iodine atom from ____ in a reaction catalyzed by selenium dependeny iodothyronine deiodinase enzymes`

T4

11

selenium is essenetial for

normal growth
metabolism

12

SEL P functions as a _______ for selenium

transport protein

13

SEL P also acts as an ______ that protects endothelial cells from damage by reactive nitrogen species

antioxidant

14

selenium is excreted in the

urine and feces

15

selenium homeostasis is maintained by the

kidneys

16

selenium deficiency related diseases

keshan
keshan beck

17

keshan dz is a cardiomyopathy that affect young women and children in a selenium def ____

china

18

keshan beck is characterized by the degeneration of ______

cartilage between joints

19

keshan beck affects ages

5-13

20

severe forms of keshan beck may result in

dwarfism

21

clinical indications for selenium supplementation

HIV AIDS

22

low levels of plasma selenium have ben associatd wtih a significantly increase risk of death from

HIV

23

early signs of selenosis (selenium toxicity)

brittle nails
hair loss
dermatitis

24

death due to acute selenosis results from what?

multiple organ failure

25

the most freq reported sx of chronic selenosis are

hair and nail brittleness/loss
n/v/d
skin rashes
garlic breath
fatigue
irritability
nervous system abn

26

selenium deficiency can trigger or worsen hypothyroidism in those with severe _____ deficiency

iodine

27

asses ____ clippings for Se status

toenail clippings