Serotonin and Dopamine Flashcards Preview

Pharmacology > Serotonin and Dopamine > Flashcards

Flashcards in Serotonin and Dopamine Deck (43):
1

5-HTP mechanism of action

precursor for serotonin (5HT)

2

5-HTP indication

depression

3

Buspirone mechanism of action

5-HT1A partial agonist

4

Buspirone indication

Anxiety/depression

5

Buspirone side effects

Early increase in anxiety

6

Sumatriptan mechanism of action

5-HT1D agonist

7

Sumatriptan indication

Migraines

8

Sumatriptan side effects

Coronary vasoconstriction
Contraindication: pts with coronary artery disease

9

Risperidone mechanism of action

5HT2A/2C antagonist

10

Risperidone indication

depression, schizophrenia with psychosis

11

Risperidone side effects

weight gain
akathisia

12

Odansetron mechanism of action

5-HT3 antagonist

13

Odansetron indication

Chemotherapy induced emesis

14

Fluoxetine mechanism of action

SSRI

15

Fluoxetine indication

Depression, OCD, anxiety, panic disorder, PTSD, social phobia

16

Fluoxetine side effects

Sexual dysfunction
Insomnia

17

Sertraline mechanism of action

SSRI

18

Sertraline indication

Depression, OCD, anxiety, panic disorder, PTSD, social phobia

19

Sertraline side effects

Sexual dysfunction
Insomnia

20

L-DOPA mechanism of action

Dopamine precursor

21

L-DOPA indication

Parkinson's disease

22

L-DOPA side effects

Arrhythmia/Dyskinesia

23

Bromocriptine mechanism of action

D2 agonist

24

Bromocriptine indication

Parkinson's disease

25

Carbidopa mechanism of action

Aromatic acid decarboxylase inhibitor

26

Carbidopa indication

Parkinson's disease

27

Carbidopa side effects

Same as L-DOPA
Arrhythmia/Dyskinesia

28

Selegiline mechanism of action

MAO-B inhibitor

29

Selegiline indication

Parkinson's disease

30

Tolcapone mechanism of action

COMT inhibitor

31

Tolcapone indication

Parkinson's disease

32

Methylphenidate mechanism of action

Dopamine reuptake inhibitor

33

Methylphenidate indication

ADHD

34

Methylphenidate side effect

Tachycardia (amphetamine)

35

Metaclopramide mechanism of action

D2 antagonist

36

Metaclopramide indication

Nausea

37

Metaclopramide side effect

Akathisia

38

Haloperidol mechanism of action

D2 antagonist

39

Haloperidol indication

Psychosis

40

Haloperidol side effects

Extra-pyramidal motor disturbances

41

Trazadone mechanism of action

5HT2A/2C antagonist and SSRI

42

Trazadone indication

Anxiety and depression

43

Trazadone side effects

Suicidality early after initiation
"I'm (traza)done with this shit"