Shocks Flashcards
Which molecures released in septic shock- and what the overall effect
Histamin, Heparin, Bradykinin, Leukotrienes, Prostaglandins
Vasodilation
what the effect of vasodilation on the heart
low SVR»_space; low Afterload»_space; increased CO
what will be the effect on the left and right artium in septic shock?
What pressures will they presnet
left atria- PCWP
right atria- Cental venous pressure (CVP)
Both will go down in septic shock
what is Mixed venous oxygen saturation (MVO2%)?
what it present?
what will happend in septic shock?
1+2. how much oxygen return to the heart after met the tissue needs
3. High = the tissues did not used the O2
What are the four SIRS criteria to diagnose sepsis?
- Tm > 38
- HR >90 BM
- RR > 20 min or pCO2 < 32 mmHg
- WBC > 12k or < 4k
High or low?
Bicrbonate levels in Lactic acidosis
low
what broad specturm antiobtiocs given to pt with sepsis?
also cover MRSA + pseudomonas
Ceftazidime & vancomycin or piperacillin and tazobactam
how to calculate Mean atrial pressure (MAP)
1/3 systole + 2/3 diastole
Drug of choice for pt with hypotensive sepsis
NE
Neurogenic Shock
Which neurologic system will be effected in spinal cord injury in thoracic levels?
what happened to SVR and CO
Sympathtic trunk- knockout
impact on vascular resistance- SVR + CO will go down
Who will get Cardiogenic shock
and what will happend to the CO + SVR
Post-MI
Temponade
CHF
CO- go down
SVR- go up
what will happend to CVP (right atria pressure)
PCWP (left atria pressure)
in cardiogenic shock
both up
what will happend to the MVO2S%
will be low
כמה חמצן חזר ללב אחרי שעבר פרפוזיה לרקמות- מאפיין תפוקת לב ירידה (שהוא נ
Hypovoulemic shock
what happens to:
* SVR
* CO
* CVP (right atria)
* PCWP (left atria)
- CO- go down
- SVR- go up
- CVP (right atria) + PCWP (left atria)- go down
what will happend to mixed venous oxygen saturation ? in hypovoulemic shock
MVO2S%
will go down- low CO
