STEP 2: DERM DECK 1 Flashcards
(41 cards)
Actinic keratosis of the scalp
**Frontal and parietal scalp of a male older adult
Multiple, partially confluent, hyperpigmented and hypopigmented macules of different size are visible. Some of these lesions have scaling, and some are covered in yellow to black-brown crusts.
These findings are characteristic of actinic keratosis.**
Lesions may either regress, persist, or progress to cutaneous squamous cell carcinoma (SCC).
The degree of epithelial dysplasia determines the risk of cutaneous squamous cell carcinoma.
Actinic keratosis
Multiple scaly lesions on erythematous s
Right hand of an older patient
Lesions may either regress, persist, or progress to cutaneous squamous cell carcinoma (SCC).
The degree of epithelial dysplasia determines the risk of cutaneous squamous cell carcinoma.
Actinic cheilitis
Four photographs of the lips of different patients (A. B, C, D)
In all patients, there is a loss of distinction of the vermillion border either focally (lower lip in C) or circumorally.
The angles of mouth (oral commissures) are characteristically spared.
A - A brown scaly lesion is visible on the lower lip.
B - The lower vermillion border is edematous. A grayish-white macule can be seen on the lower lip. Superficial ulceration with crusting is visible on the mid-upper and lower lips. Scaling and fissuring are also visible.
C - The lower vermillion border is edematous. The lower lip appears dry and brownish scales are visible laterally.
D - Multiple brown macules can be seen.
These features depict the various presentations of actinic cheilitis, a precancerous lesion of the skin caused by chronic sun damage.
Actinic keratoses are caused by
exposure to UV light.
Colonization of the yeast Malassezia furfur (previously known as Pityrosporum ovale) in areas with sebaceous glands
Seborrheic dermatitis
What is seborrheic dermatitis?
A common chronic inflammatory skin condition affecting areas with high sebaceous glands.
Affects the scalp and face primarily.
What are the common symptoms of seborrheic dermatitis?
Burning and/or itching.
Symptoms also include erythematous patches, scaling, and greasy yellow crusts.
What is the typical treatment for seborrheic dermatitis?
Topical antifungal agents, with possible use of anti-inflammatory agents based on severity.
Ongoing management may include pharmacotherapy to prevent flares.
What is infantile seborrheic dermatitis also known as?
Cradle cap.
It usually appears within the first 3 months after birth.
What is the prognosis for seborrheic dermatitis?
Chronic, recurrent course with flares requiring intermittent treatment.
Most cases can be managed effectively.
What is the prevalence of seborrheic dermatitis in the general population?
Approximately 2–5% worldwide.
Epidemiological data primarily refers to the US.
Which factors are associated with the etiology of seborrheic dermatitis?
Malassezia species, hormonal and immunological factors, climate.
The exact etiology remains unknown.
What are the endogenous precipitants of seborrheic dermatitis?
Psychological stress, fatigue, sleep deprivation, hormonal changes.
These factors can exacerbate the condition.
What are the exogenous precipitants of seborrheic dermatitis?
Climate, trauma, medication.
Symptoms may improve in summer and worsen in winter.
What is the typical appearance of seborrheic dermatitis in adults and adolescents?
Erythematous patches or plaques with scaling and greasy yellow crusts.
Can also include flaking and hyperpigmentation/hypopigmentation.
How is the diagnosis of seborrheic dermatitis made?
Diagnosis is clinical.
Skin biopsy may be needed for diagnostic uncertainty.
What are the differential diagnoses for seborrheic dermatitis?
Atopic dermatitis, contact dermatitis, dermatophyte infections, rosacea, candidiasis.
Each has distinct clinical features.
What is the recommended management approach for seborrheic dermatitis?
Avoid precipitating factors, initiate treatment with topical antifungals, consider corticosteroids for moderate to severe cases.
Systemic therapy may be needed for widespread disease.
What are potential complications of seborrheic dermatitis?
Exacerbation leading to generalized erythroderma and secondary bacterial infection.
Complications are not exhaustive.
When does infantile seborrheic dermatitis typically resolve?
Usually resolves without intervention by 12 months of age.
It is a benign condition.
What advice can be given to parents regarding infantile seborrheic dermatitis?
The condition is benign and often resolves spontaneously.
Parents can remove scales with gentle washing and softeners.
What is a severe form of infantile seborrheic dermatitis?
Desquamative erythroderma (Leiner disease).
It includes symptoms like recurrent diarrhea and failure to thrive.
Fill in the blank: The pathophysiology of seborrheic dermatitis is not yet fully _______.
understood.