STEP2: PEDS AUTOIMMUNE Flashcards
(2 cards)
Criteria for kawasaki
fever for ≥ 5 days and ≥ 4 of the following: erythema, edema, or desquamation of hands and feet (including the palms and soles), a polymorphous rash (originating on the trunk), painless bilateral injected conjunctivitis without exudate, oropharyngeal mucositis (strawberry tongue, cracked and red lips), and cervical lymphadenopathy (mostly unilateral).
What is the treatment for kawasaki
A single dose of high-dose intravenous immunoglobulin (IVIG) is recommended for patients with Kawasaki disease to reduce the risk of coronary artery aneurysms. It is most effective within the first 10 days of disease onset. In addition to IVIG, patients should receive high-dose oral aspirin to treat other inflammatory symptoms (e.g., arthritis) until the fever subsides. Treatment is then continued with a lower dosage for its antiplatelet effect to prevent myocardial infarction and ischemia. While aspirin is usually contraindicated in children because of its association with Reye syndrome, Kawasaki disease is a rare exception in which it is indicated. Patients should also undergo echocardiography at diagnosis, as well as at 2 weeks and 6–8 weeks after onset, to evaluate for coronary artery aneurysms.
