Strep pneu, pertussis, legionella, mycobacterium Flashcards Preview

Micro > Strep pneu, pertussis, legionella, mycobacterium > Flashcards

Flashcards in Strep pneu, pertussis, legionella, mycobacterium Deck (31):
1

main characteristics of strep pnemonia

gram +, diploccoci, aerotolerant aneorobe

2

which pathogen is non spore forming, encapsulated, and is the main cause of pnemonia

Strep pneumoniae

3

Strep pnemoniae has what hemolysis pattern and what result on a catalase text

Alpha hemolysis, catalase neg. (gram neg)

4

how can you positivley identify strep pnemonia

its susceptibility to optochin

5

how does strep pnemonia get entry into host

many people are carries and gets into lower airway

6

explain the 4 stage pathogenesis of strep pnemoniae

1 - alveoli fill w/fluid
2- influx of neutrophils (inflammation)
3- neitrophils consolidate/firmer
4 - phagocytosis of pathogen and recovery

7

otitis media is caused by what pathogen

strep pnemoniae

8

Strep pnemoniae is resistant to ?

Penicillans and other B-lactams

9

when would should you recieve a vaccine for strep pnemoniae

as a baby (2-15 months)
over age of 65

10

what pathogen can be identified because of its cysteine requirement

Legionella pneumophila

11

what are the main characteristics of legionella pneumophila

gram (-), pleomorphic rods, obligate aerobe

12

what color would a gram negative pathogen stain on a gram stain

pink

13

how does one encounter legionella pheumophila

contaminated water

14

how does legionella pneumophila multiply/spread

they are NOT killed by phagocytes, but actually MULTIPLY inside of the macrophages

15

how do you treat legionella pneumophilla

drugs w/ good intracellular penetration (cuz inside macrophages)
-penicillans dont work

16

LPS is found in what type of pathogens

gram negative

17

main characteristics of Bordetalla pertussis

gram (-) rod, obilgate aerobe

18

what does bordetella pertussis cause

contagious whooping cough

19

what is the resovoir for pertussis

infected adults

20

where does pertussis like to colonize

nasopharynx

21

what is the difference b/w Bordetella pertussis and parapertussis

B. pertussis has a pertussis toxin
-parapertussis has NO toxin

22

what are the 3 clinical stages of pertussis

1 - catarrhal stage (cold symptoms) - very contagious
2- paroxysmal stage - coughing attacks
3 - convalescent stage - recovery

23

what is the mechanism and what are the 2 vaccines for pertussis

vaccines have ACELLULAR pertussis
-dTaP
-Tdap

24

what 2 diseases can be caused by mycobacterium species

M. Tuberculosis
M. Leprosy

25

what pathogens are "acid fast bacteria"

mycobacterium

26

what is secondary tuberculosis

its when a latent Tb lesion becomes reactivated

27

what is the pathogenesis of Tb

they are phagocytized and multiply w/in macrophages forming granulomas then eventually lesions

28

how do you diagnose Tb ?

inject the killed antigen "tuberculin or PPD" intradermally
-wait 48 hours and see if forms granuloma

29

M. leprosy has similar pathogenesis and immunology as Tb, thus it forms what on skins as disease progresses

granulomas

30

what are the 2 forms of M leprosy and what is the severity of each

Tuberculoid leprosy - mild flat/sessile lesions
Lepromatous Leprosy - severe w/many deforming lesions

31

what pathogen can not be cultured in vitro ?

M. leprae