THE PERIPHERAL NERVOUS SYSTEM Flashcards

(63 cards)

1
Q

What are the nerves of the peripheral nervous system? (2)

A

consist of nerve fibres (axons and dendrons) arranged in bundles, protected by connective tissue sheaths.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what do the peripheral nervous system nerves consist of? (2)

A

-sensory neurones carrying impulses to the CNS
-motor neurones carrying impulses to muscles and glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the somatic nervous system? (1)

A

the system of motor neurones carrying impulses to muscles controlling voluntary (conscious) actions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the autonomic nervous system? (1)

A

the network of motor neurones carrying impulses to the heart, smooth muscle and glands controlling involuntary (unconscious actions)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the parts of the ANS? (2)

A

-the sympathetic nervous system
-the parasympathetic nervous system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are the roles of the sympathetic nervous system? (9)

A

-more active in times of stress to produce ‘fight or flight’ responses
-at their junctions with effector tissues the neurones release noradrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the roles of the parasympathetic nervous system? (2)

A

-concerned with conservation of energy and the replacement of body reserves
-at their junctions with effector tissues the neurones release acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are the response of the sympathetic nervous system? (6)

A

-increases ventilation
-causes widening (ventilation) of the tissues
-has no effect on the tear glands
-has no effect on the salivary glands
-slows peristalsis
-constricts bladder sphincter muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are the responses of the parasympathetic system? (6)

A

-decreases ventilation rate
-causes constriction (narrowing) of the pupils
-causes the secretion of tears
-cause the secretion of saliva
-accelerates peristalsis
-causes relaxation of the sphincter muscles of the bladder and contraction of the muscular wall of the bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the different types of neurones? (3)

A

-motor neurones
-interneurons
-sensory neurones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

describe the structure of a motor neurone. (1)

A

have many dendrites which bring impulses towards the cell body, and a single long, axon, which carries impulses away from the cell body.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

describe the structure of an interneuron. (1)

A

have numerous short fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

describe the structure of sensory neurones. (1)

A

have a single long dendron, which brings impulses towards the cell body, and a single long axon, which carries impulses away

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what surrounds neurones? (1)

A

different types of supporting cells called neuroglia cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the most common surrounding cells? (1)

A

they care called schwann cells, these wrap themselves around the fibres, forming a structure called a myelin sheath, the junction is called a node of ranvier.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is a node of ranvier? (1)

A

A small gap in the myelin sheath surrounding an axon.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is an impulse? (1)

A

The impulse is not an electrical current, it is a momentary reversal in electrical difference in the membrane. It is a change in the amounts of positively and negatively charged ions between the inside and outside of the membrane of a nerve fibre.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is an impulse transmitted? (1)

A

This reversal travels from one end of the neurone to the other in a fraction of a second, between conduction of cone impulse and the next, the neurone is said to be resting.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What occurs during a resting interval? (1)

A

The membrane of a neurone actively creates and maintains an electrical potential difference between the inside and the outside of the fibre.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What two processes produce the resting potential difference across the neurone membrane? (2)

A

-active transport
-facilitated diffusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Describe the active transport process that produces the resting potential difference. (1)

A

Active transport of potassium ions in across the membrane, and of sodium ions out across the membrane. The ions are transported by a Na+ - K+ pump, with transfer of energy from ATP. so potassium and sodium ions gradually concentrate on opposite sides of the membrane, this makes no change to the potential difference across the membrane.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Describe the facilitated diffusion process to produce the resting potential difference. (1)

A

Facilitated diffusion of K+ ions out and Na+ ions back in, the membrane is more permeable to K+ions flowing out than to Na+ ions returning. This causes the tissue fluid outside the neurone to contain many more positive ions than are present in the cytoplasm inside. As a result, the inside becomes more and more negatively charged compared with the outside, the resting neurone is said to be polarised.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is an impulse triggered by? (1)

A

An impulse, or action potential is triggered by a stimulus received at a receptor cell or sensitive nerve ending. The energy transferred by a stimulus causes a temporary and local reversal of the resting potential, the result is that the membrane is temporarily depolarised.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
How does a brief depolarisation occur? (1)
The change in potential across the membrane occurs through pores in the membrane, called ion channels because they can allow ions to pass through, during a resting potential these channels are closed. The energy of the stimulus first opens the gates of the sodium channels in the cell surface membrane. This allows sodium ions to diffuse in, down their electrochemical gradient, so the cytoplasm inside the neurone fibre quickly becomes progressively more positive with respect to the outside.
26
Explain the first stage of ion movements during the action potential. (1)
During the resting potential the ion channels for Na+ ions and K+ ions are both closed.
27
Explain the second stage of ion movements during the action potential. (1)
Na+ channels open and Na+ ions rush in (by diffusion)
28
Explain the third stage of ion movements during the action potential. (1)
Interior axon becomes increasingly more positively charged with respect to the outside.
29
Explain the fourth stage of ion movements during the action potential. (1)
Equally suddenly Na+ channels close at the same moment as K+ channels open and K+ ions rush out (by diffusion)
30
Explain the fifth stage of ion movements during the action potential. (1)
Interior of axon now starts to become less positive again
31
Explain the first stage of ion movements during the action potential. (1)
32
Explain the sixth stage of ion movements during the action potential. (1)
Na+/K+ pump starts working, together with facilitated diffusion, so that the resting potential is re-established
33
What is a refractory period? (1)
A brief period following the passage of an action potential, the neurone fibre is no longer excitable. It only lasts 5-10 milliseconds
34
What happens during the refractory period? (1)
During this time, firstly there is a large excess of sodium ions inside the neurone fibre and further influx is impossible. As the resting potential is progressively restored, however, it becomes increasingly -possible for an action potential to be generated again
35
What is the threshold of stimulation? (1)
A stimulus must be at or above a minimum intensity in order initiate an action potential at all
36
37
Where on a neurone is the axon membrane exposed? (1)
Only at the nodes of ranvier
38
What is the saltatory conduction? (1)
Conduction of an action potential along a nerve fibre by jumping from node to node, thus increasing the speed
39
What is a synapse? (1)
A tiny gap between two neurones that prevent two neurones from touching
40
Describe the structure of a synapse. (1)
Synapses consist of the the swollen tip (synaptic knob) of the axon of one neurone (pre-synaptic neurone) and the dendrite or cell body of another neurone (post-synaptic neurone)
41
What is the effect of the synaptic cleft? (1)
The practical effect of the synaptic cleft is that an action potential cannot cross it. Here, transmission occurs by specific chemicals (transmitter substances)
42
What is acetylcholine? (1)
A commonly occurring transmitter substance at synapses
43
What are cholinergic neurones? (1)
Neurones releasing acetylcholine at their synapses
44
What is noradrenaline? (1)
A commonly occurring transmitter substance at synapses
45
What are adrenergic neurones? (1)
Neurones releasing noadrenaline at their synapses
46
What is the first stage of synapse transmission? (1)
Impulse arrives at synapse and triggers Ca2+ ion entry
47
What is the second stage of synapse transmission? (1)
Transmitter substance released diffuses to receptors of post-synaptic membrane
48
What is the third stage of synapse transmission? (1)
Transmitter substance binds, triggering entry of Na+ ions and action potential in post-synaptic membrane
49
What is the fifth stage of synapse transmission? (1)
Re-formation of transmitter substance vesicles
50
What is the sixth stage of synapse transmission? (1)
Enzymic inactivation of transmitter
51
What are inhibitory transmitters? (1)
If a transmitters effect is to cause the membrane to be less likely to reach the threshold value (make the potential difference more negative)
52
What is an exciting transmitter? (1)
If the effect is to cause the membrane to be more likely to reach the threshold value (that is to make the potential difference less negative)
53
What are the types of transmitters? (2)
-inhibitory -excitatory
54
What transmitter opens Na+ channels? (1)
The transmitter glutamate (an amino acid) attached to receptor sites and causes the opening of Na+ channels
55
What occurs when Na+ channels open? (1)
The influx of Na+ ions set up tiny area of depolarisation , which are called excitatory post-synaptic potentials, these potentials make the membrane less negatively charged and more likely to reach the threshold level to trigger an action potential
56
What is the most common transmitter in the brain? (1)
The transmitter gamma-aminobutyric acid
57
What is the function of the most common transmitter in the brain? (1)
When it attaches to receptor sites it causes the opening of Cl- ion channels which sets up tiny areas of further polarisation that are called inhibitory post-synaptic potentials, these potentials make the membrane more negatively. Charged and less likely to reach the threshold level to trigger an action potential
58
How can synapses be manipulated? (1)
Because they are not contained within myelin sheaths they can be manipulated
59
What are some examples of chemical intervention of synapses? (3)
Lidocaine, nicotine and cobra venom
60
What is the function of lidocaine? (1)
Blocks voltage-gated Na+ ion channels
61
What is the effect of lidocaine? (1)
In the synapse it means the post-synaptic membrane is not able to depolarise so no action potentials can travel to the brain to record pain. The pain receptors themselves need to depolarise to initiate pain signals so they never respond
62
What is the function of nicotine? (1)
Its ability to bind with acetylcholine receptor sites in synapses
63
What is the effect of nicotine? (1)
This blockage causes more ACh to be produced and a feeling of greater alertness as synapses as excited, it causes the brain realise another neurotransmitter called dopamine